Treatment of Port Wine Stains with Intense Pulsed Light: A Prospective Study

Ho, W.S; Ying, S.Y; Chan, Pik Chu; Chan, Henry Ho-lung

doi:10.1111/j.1524-4725.2004.30260.x

Cited by 41 publications

(39 citation statements)

References 26 publications

(55 reference statements)

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“…In its favour, the IPL treatment did not result in any notable side effects, even at the higher fluence setting (34 J/cm 2 ), which is a potential advantage over the alexandrite laser. The level of improvement seen here is in keeping with previous studies, which have found that up to 50% of previously treated CM patients will respond to IPL treatment, although complete clearance was rare [2][3][4][5]. This was also the case in previously untreated patients [6].…”

Section: Response Of CM Colour To Test Patchessupporting

confidence: 78%

“…However, complete CM clearance rates have remained around 15% despite the use of later generation PDL's with longer wavelengths and deeper penetration [1]. Therefore other laser and non-laser systems have been used in an attempt to improve CM clearance, including intense pulsed light (IPL) [2][3][4][5][6], the KTP laser [7,8], and the long-pulsed Nd:YAG laser [9].…”

Section: Introductionmentioning

confidence: 99%

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A direct comparison of pulsed dye, alexandrite, KTP and Nd:YAG lasers and IPL in patients with previously treated capillary malformations

2008

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Alexandrite laser treatment was the most effective, but resulted in hyperpigmentation and scarring in four patients, probably due to its deeper penetration and lower specificity for oxyhaemoglobin causing non-specific dermal damage. Double passing of the PDL can result in further CM fading even in previously treated patients. Videomicroscopy measurements of capillary diameter before treatment may be predictive of the likelihood for patient's to respond to laser treatment.

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Section: Response Of CM Colour To Test Patchessupporting

confidence: 78%

Section: Introductionmentioning

confidence: 99%

A direct comparison of pulsed dye, alexandrite, KTP and Nd:YAG lasers and IPL in patients with previously treated capillary malformations

2008

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“…In a few studies, IPL has shown promising results for the treatment of PWS. [13][14][15][16][17] As both PDL ⁄LPDL and IPL treatments are currently available, comparative studies are needed. So far, no studies have compared PDL ⁄LPDL with IPL in the treatment of PWS in a randomized clinical trial.…”

Section: Discussionmentioning

confidence: 99%

Pulsed dye laser vs. intense pulsed light for port-wine stains: a randomized side-by-side trial with blinded response evaluation

Faurschou

Togsverd‐Bo

Zachariae

et al. 2009

British Journal of Dermatology

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Background Pulsed dye lasers (PDLs) are considered the treatment of choice for port-wine stains (PWS). Studies have suggested broadband intense pulsed light (IPL) to be efficient as well. So far, no studies have directly compared the PDL with IPL in a randomized clinical trial. Objectives To compare efficacy and adverse events of PDL and IPL in an intraindividual randomized clinical trial. Methods Twenty patients with PWS (face, trunk, extremities; pink, red and purple colours; skin types I-III) received one side-by-side treatment with PDL (V-beam Perfecta, 595 nm, 0AE45-1AE5 ms; Candela Laser Corporation, Wayland, MA, U.S.A.) and IPL (StarLux, Lux G prototype handpiece, 500-670 and 870-1400 nm, 5-10 ms; Palomar Medical Technologies, Burlington, MA, U.S.A.). Settings depended on the preoperative lesional colour. Treatment outcome was evaluated by blinded, clinical evaluations and by skin reflectance measurements. Results Both PDL and IPL lightened PWS. Median clinical improvements were significantly better for PDL (65%) than IPL (30%) (P = 0AE0004). A higher proportion of patients obtained good or excellent clearance rates with the PDL (75%) compared with IPL (30%) (P = 0AE0104). Skin reflectance also documented better results after PDL (33% lightening) than IPL (12% lightening) (P = 0AE002). Eighteen of 20 patients preferred to receive continued treatments with PDL (P = 0AE0004). No adverse events were observed with PDL or IPL. Conclusions Both the specific PDL and IPL types of equipment used in this study lightened PWS and both were safe with no adverse events. However, the PDL conveyed the advantages of better efficacy and higher patient preference.

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“…These authors found that the investigated spectra provided homogeneous heating in the entire vessel that was sufficient for coagulating vessels > 60 mm. There is evidence in the literature for successful treatment of essential telangiectasias [30], rosacea [31,32], port-wine stains (PWS) [33][34][35][36][37], spider nevi [38], angiomas [39][40][41], and erythrosis [30]. For the treatment of essential telangiectasias, PWS, and rosacea level of evidence IIB is reached.…”

Section: Vascular Lesionsmentioning

confidence: 99%

Intense pulsed light (IPL): A review

et al. 2010

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Background: Intense pulsed light (IPL) devices use flashlamps and bandpass filters to emit polychromatic incoherent high-intensity pulsed light of determined wavelength spectrum, fluence, and pulse duration. Similar to lasers, the basic principle of IPL devices is a more or less selective thermal damage of the target. The combination of prescribed wavelengths, fluences, pulse durations, and pulse intervals facilitates the treatment of a wide spectrum of skin conditions. Objective: To summarize the physics of IPL, to provide guidance for the practical use of IPL devices, and to discuss the current literature on IPL in the treatment of unwanted hair growth, vascular lesions, pigmented lesions, acne vulgaris, and photodamaged skin and as a light source for PDT and skin rejuvenation. Methods: A systematic search of several electronic databases, including Medline and PubMed and the authors experience on intense pulsed light. Results: Numerous trials show the effectiveness and compatibility of IPL devices. Conclusion: Most comparative trials attest IPLs similar effectiveness to lasers (level of evidence: 2b to 4, depending on the indication). However, large controlled and blinded comparative trials with an extended follow-up period are necessary. Lasers Surg. Med. 42:93-104, 2010.

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Treatment of Port Wine Stains with Intense Pulsed Light: A Prospective Study

Abstract: Intense pulsed light can be effective in treating port wine stains in Asian patients. In experienced hands, complications can be low and should be considered as one of the therapeutic options.

Cited by 41 publications

References 26 publications

A direct comparison of pulsed dye, alexandrite, KTP and Nd:YAG lasers and IPL in patients with previously treated capillary malformations

A direct comparison of pulsed dye, alexandrite, KTP and Nd:YAG lasers and IPL in patients with previously treated capillary malformations

Pulsed dye laser vs. intense pulsed light for port-wine stains: a randomized side-by-side trial with blinded response evaluation

Intense pulsed light (IPL): A review

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