Treatment of premenstrual tension syndrome with Vitex agnus castus controlled, double-blind study versus pyridoxine

Lauritzen, C; Reuter, Helmuth; Repges, Rudolf; Böhnert, K.-J.; Schmidt, Ulrich

doi:10.1016/s0944-7113(97)80066-9

Cited by 95 publications

(61 citation statements)

References 9 publications

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“…Treatment with VAC results in few unwanted side effects, and is therefore a popular alternative therapy for women who do not respond to or tolerate the hormonal or psychotropic drugs. The last decade has provided several successful clinical trials supporting the use of VAC for treatment of PMS (Lauritzen et al, 1997;Berger et al, 2000;Loch et al, 2000;Schellenberg, 2001;Atmaca et al, 2003).…”

Section: Introductionmentioning

confidence: 99%

Activation of the μ-opiate receptor by Vitex agnus-castus methanol extracts: Implication for its use in PMS

Webster

Chen³

et al. 2006

Journal of Ethnopharmacology

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Section: Introductionmentioning

confidence: 99%

Activation of the μ-opiate receptor by Vitex agnus-castus methanol extracts: Implication for its use in PMS

Webster

Chen³

et al. 2006

Journal of Ethnopharmacology

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“…However, a systematic review (Budeiri et al 1996) of placebo-controlled trials of evening primrose oil found no significant evidence that it is helpful in treating PMS. In recent years, two PMS studies (Schellenberg, 2001;Lauritzen et al 1997) reported that chaste-tree berry (Vitex agnus-castus) shows some benefit over placebo or vitamin B 6 in comparison to baseline. In another study (Atmaca et al 2003), the outcome indicated that patients with PMDD responded well to treatment with combined selective serotonin reuptake inhibitor (SSRI) (fluoxetine) and Vitex agnus castus.…”

Section: Non-pharmacologic Treatments Of Pmsmentioning

confidence: 99%

A Controlled Trial of Chinese Herbal Medicine for Premenstrual Syndrome

Chou¹,

Morse²,

Xu³

et al. 2009

Deutsche Zeitschrift für Akupunktur

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Premenstrual syndrome is a common disorder troubling many women during their reproductive years. The Chinese have been using herbal medicines to treat menstrual cycle related symptoms for centuries. Traditional Chinese medicine provides the aetiology and pathogenesis of the symptoms of this disorder by applying Pattern Identification to diagnose the signs and symptoms of individual patients and to design individualised treatments which seek to address the entire pattern/s of disharmony. It follows that PMS, which has many symptoms and an idiosyncratic nature, is precisely an area for which Chinese medicine is most suitable. The aim of this study is to scientifically evaluate the effectiveness of Chinese herbal medicine on Australian women for the treatment of PMS within the theoretical frame-work of TCM. A double-blind randomized placebo-controlled crossover clinical trial was conducted by a qualified Chinese herbal practitioner and pharmacist. Following two months confirmatory assessment, sixty-one subjects were assigned randomly into two groups within different TCM patterns of Liver Qi Stagnation, Liver and Kidney Yin Deficiency, Liver and Spleen Disharmony and Heart and Spleen Deficiency. Herbal medicine (n=31) and placebo (n=30) were provided sequentially for a period of three months. There were significant differences (p < .01) in scores after three months of treatment between Chinese herbal medicine and placebo in premenstrual physical and psychological symptoms, depression, anxiety and anger, but with no difference in perceived stress (p > .05). There were highly significant reductions (p< .001) in all assessments in both groups except that a significant result (p < .05) was recorded on perceived

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“…Vitex is often used together with vitamin B 6 , which has also proven to be quite helpful for resolving hormonal acne, although one comparative trial found that vitex was superior to vitamin B 6 for helping patients with symptoms of premenstrual syndrome. 38 When androgens are a problem in acne vulgaris, Serenoa repens (saw palmetto) fruit is the first herb most clinicians use. If polycystic ovarian syndrome or documented high serum androgens are present, saw palmetto should be considered to help offset the negative effects of excessive androgens.…”

Section: Hormonal Acnementioning

confidence: 99%

Herbal Medicine for Acne Vulgaris

Yarnell¹,

Abascal²

2006

Alternative and Complementary Therapies

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Researchers examining the efficacy of medical procedures make assumptions about the nature of placebo. From these assumptions they select the sham interventions to be used in their trials. However, placebo is not well defined. A number of definitions are contradictory and sometimes misleading. This leads to problems in sham-controlled studies of medical procedures and difficulties interpreting their results. The author explores some of the contradictory definitions of placebo and assumptions and consequences of these. Principal among these is the assumption that the placebo is inert when it is not, which introduces bias against the tested medical procedures and devices. To illustrate the problem, the author examines the use of sham procedures in clinical trials of the medical procedures surgery and acupuncture in which the sham was assumed to be inert but was not. Trials of surgery and acupuncture should be re-examined in light of this.

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Treatment of premenstrual tension syndrome with Vitex agnus castus controlled, double-blind study versus pyridoxine

Cited by 95 publications

References 9 publications

Activation of the μ-opiate receptor by Vitex agnus-castus methanol extracts: Implication for its use in PMS

Activation of the μ-opiate receptor by Vitex agnus-castus methanol extracts: Implication for its use in PMS

A Controlled Trial of Chinese Herbal Medicine for Premenstrual Syndrome

Herbal Medicine for Acne Vulgaris

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