Treatment of primary choriocarcinoma of lung

Паршин, В Д; Kogan, E. A.; Mirzoyan, O. S.; Starostin, A. V.; Seredin, V P

doi:10.17116/hirurgia20183243-45

“…Chemotherapy should be started as soon as the results of the pathological evaluation and biological markers were known. We can use chemotherapy including bleomycin, etoposide, cisplatin, surgery and postoperative radiotherapy, and the prognosis will be improved [11] .…”

Section: Discussionmentioning

confidence: 99%

Choriocarcinoma syndrome of primary pulmonary choriocarcinoma after lung lobe resection: A case report and review of the literature

Chen

¹

,

Zhao

²

,

Liu

³

et al. 2021

Preprint

0

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Introduction: Primary pulmonary choriocarcinoma (PPC) is extremely rare, especially in males. It is characterized by a poor response to therapy and shortened survival times. Here, we report a PPC case which was complicated by choriocarcinoma syndrome (CS) and a review of the literature.Case presentation: A 59-year-old man with 30-pack-year smoking history was referred to our hospital because of hemoptysis and chest pain. Positron emission tomography-computed tomography (PET-CT) showed multiple bilateral pulmonary nodules and multiple metastases throughout the body. The patient underwent single-port thoracoscopic wedge resection of the right lung upper lobe. Histological examinations verified the diagnosis of choriocarcinoma. Three days after the operation, the patient developed massive hemoptysis. A bronchoscopic examination showed bleeding from the bilateral main bronchus. Despite management in the intensive care unit (ICU), the patient died two weeks after surgery. Conclusions: A rapid and correct diagnosis of PPC is necessary. When the patient has massive hemoptysis, we should be alert to the occurrence of CS. Surgery and modified chemotherapy, based on the physical condition of the patient, may currently be the best therapy for PPC.

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“…Especially when we found that the patient has massive hemoptysis, we should be alert to the occurrence of CS. We can use chemotherapy including bleomycin, etoposide, cisplatin, surgery and postoperative radiotherapy, and the prognosis will be improved [11] .…”

Section: Discussionmentioning

confidence: 99%

Choriocarcinoma Syndrome of Primary Pulmonary Choriocarcinoma after Lung Lobe Resection: A Case Report and Review of the Literature

Chen

¹

,

Zhao

²

,

Liu

³

et al. 2021

Preprint

0

View full text Add to dashboard Cite

Introduction: Primary pulmonary choriocarcinoma (PPC) is extremely rare, especially in males. It is characterized by a poor response to therapy and shortened survival times. Here, we report a PPC case which was complicated by choriocarcinoma syndrome (CS) and a review of the literature.Case presentation: A 59-year-old man with 30-pack-year smoking history was referred to our hospital because of hemoptysis and chest pain. Positron emission tomography-computed tomography (PET-CT) showed multiple bilateral pulmonary nodules and multiple metastases throughout the body. The patient underwent single-port thoracoscopic wedge resection of the right lung upper lobe. Histological examinations verified the diagnosis of choriocarcinoma. Three days after the operation, the patient developed massive hemoptysis. A bronchoscopic examination showed bleeding from the bilateral main bronchus. Despite management in the intensive care unit (ICU), the patient died two weeks after surgery. Conclusions: A rapid and correct diagnosis of PPC is necessary. When the patient has massive hemoptysis, we should be alert to the occurrence of CS. Surgery and modified chemotherapy, based on the physical condition of the patient, may currently be the best therapy for PPC.

show abstract

“…Chemotherapy should be started as soon as the results of the pathological evaluation and biological markers are known. Chemotherapy, including bleomycin, etoposide, and cisplatin; surgery; and postoperative radiotherapy are all acceptable treatments that will improve the prognosis [11] .…”

Section: Discussionmentioning

confidence: 99%

Choriocarcinoma Syndrome of Primary Pulmonary Choriocarcinoma After Lung Lobe Resection: a Case Report and Review of the Literature

Chen

¹

,

Zhao

²

,

Liu

³

et al. 2021

Preprint

0

View full text Add to dashboard Cite

Introduction: Primary pulmonary choriocarcinoma (PPC) is extremely rare, especially in males. It is characterized by a poor response to therapy and shortened survival times. Here, we report a PPC case that was complicated by choriocarcinoma syndrome (CS) and present a review of the literature.Case presentation: A 59-year-old man with a 30-pack-year smoking history was referred to our hospital because of haemoptysis and chest pain. Positron emission tomography-computed tomography (PET-CT) showed multiple bilateral pulmonary nodules and multiple metastases throughout the body. The patient underwent single-port thoracoscopic wedge resection of the right lung upper lobe. Histological examinations verified the diagnosis of choriocarcinoma. Three days after the operation, the patient developed massive haemoptysis. A bronchoscopic examination showed bleeding from the bilateral main bronchus. Despite management in the intensive care unit (ICU), the patient died two weeks after surgery.Conclusions: A rapid and correct diagnosis of PPC is necessary. When the patient has massive haemoptysis, we should be alert to the occurrence of CS. Surgery and modified chemotherapy, based on the physical condition of the patient, may currently be the best therapy for PPC.

show abstract

Treatment of primary choriocarcinoma of lung

Cited by 3 publications

References 4 publications

Choriocarcinoma syndrome of primary pulmonary choriocarcinoma after lung lobe resection: A case report and review of the literature

Choriocarcinoma syndrome of primary pulmonary choriocarcinoma after lung lobe resection: A case report and review of the literature

Choriocarcinoma Syndrome of Primary Pulmonary Choriocarcinoma after Lung Lobe Resection: A Case Report and Review of the Literature

Choriocarcinoma Syndrome of Primary Pulmonary Choriocarcinoma After Lung Lobe Resection: a Case Report and Review of the Literature

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