Treatment of primary infertility in McCune-Albright syndrome: a case report of a successful in vitro fertilization cycle

Abstract

Objective: To report a case in which pregnancy and live birth were achieved in an infertile patient with McCune-Albright syndrome via in vitro fertilization (IVF). Design: Case report. Setting: University hospital. Patient(s): A 29-year-old woman with McCune-Albright syndrome who presented with primary infertility due to ovulatory dysfunction and bilateral tubal blockage. Intervention(s): In vitro fertilization without unilateral oophorectomy. Main Outcome Measure(s): Live birth after IVF treatment. Result(s): Fresh IVF stimulation and bilateral oocyte retrieval yielded 12 oocytes and 4 top quality embryos. Fresh single embryo transfer did not result in pregnancy. Live birth occurred after the second frozen embryo transfer cycle. Conclusion(s): In vitro fertilization can lead to ongoing pregnancy in infertile patients with McCune-Albright syndrome without requiring unilateral oophorectomy.