Treatment of pulmonary hypertension with inhaled agents in the pediatric intensive care unit

Gillis, Holly; Fischer, Gwenyth; Gupta, Sameer

doi:10.2146/ajhp170353

Cited by 1 publication

(1 citation statement)

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“…This therapy requires a special nebulizer system to be implemented and can be connected to both invasive and noninvasive support methods. Interestingly, because of the expense of iNO and the reduced cost of inhaled epoprostenol, groups have demonstrated substantial cost savings without any increase in patient harm with the use of inhaled epoprostenol 98,99 . However, at this time, iNO remains the recommended therapy for the acute management of PH 8,100 …”

Section: Pulmonary Vasodilatorsmentioning

confidence: 99%

Intensive care management of right ventricular failure and pulmonary hypertension crises

Coleman

Chartan

Mourani

2021

Pediatric Pulmonology

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Pulmonary hypertension (PH), an often unrelenting disease that carries with it significant morbidity and mortality, affects not only the pulmonary vasculature but, in turn, the right ventricle as well. The survival of patients with PH is closely related to the right ventricular function. Therefore, having an understanding of how to manage right ventricular failure (RVF) and acute pulmonary hypertensive crises is imperative for clinicians who encounter these patients. This review addresses the management of these patients in detail, addressing: (a) the pathophysiology of RVF, (b) intensive care monitoring of these patients in the intensive care unit, (c) imaging of the right ventricle, (d) intubation and mechanical ventilation, (e) inotrope and vasopressor selection, (f) pulmonary vasodilator use, (g) interventional and surgical procedures for the acutely failing right ventricle, and (h) mechanical support for RVF.

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Section: Pulmonary Vasodilatorsmentioning

confidence: 99%