Treatment of rare nodular amyloidosis on the nose: A case report

Schipper, Carlijn R.; Cornelissen, Annemiek J. M.; Welters, Carlo F.M.; Hoogbergen, Maarten M.

doi:10.1016/j.jpra.2015.07.006

Cited by 3 publications

(8 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The mean age of onset of nodular localized cutaneous amyloidosis is 55 years, with a range of 33 to 86 years [3]. The condition does not show a predilection for men versus women, nor a particular race.…”

Section: Discussionmentioning

confidence: 99%

“…Because of the extremely characteristic histopathology of amyloidosis, diagnosis is made by biopsy [3]. Histological examination of nodular amyloidosis reveals eosinophilic deposits distributed throughout the dermis.…”

Section: Discussionmentioning

confidence: 99%

“…Various treatments for nodular cutaneous amyloidosis exist. The most common method is surgical removal, specifically using a surgical shave technique [3]. In cases of facial nodular amyloidosis, the surgical technique is highly preferred [12].…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

A Rare Presentation of Nodular Amyloidosis on the Lower Back

Dokic

Subrt²,

Tschen

2019

Cureus

View full text Add to dashboard Cite

Primary localized cutaneous amyloidosis (PLCA) occurs when amyloid is deposited only within the skin and there is no evidence of systemic involvement. Nodular amyloidosis is the rarest subtype of PLCA. It typically involves the acral regions but can sometimes present on the head and neck. The condition usually presents clinically as a single tan or yellow nodule or plaque that may appear waxy. Herein, we present a rare case of a 66-year-old man with nodular amyloidosis on the lower back.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

A Rare Presentation of Nodular Amyloidosis on the Lower Back

Dokic

Subrt²,

Tschen

2019

Cureus

View full text Add to dashboard Cite

show abstract

“…In this universe, there is preferential involvement of upper airways, being the larynx the most affected organ [3,4]. Other affected sites are: skin [5,6], oral cavity [7,8], nasal cavity [9,10], pharynx [11], parotid gland [2] and ear [12,13]. No reports on multiple sites involvement in head and neck were found in literature review.…”

Section: Introductionmentioning

confidence: 99%

“…As a rare event, most of the information available in the literature are in reviews [8,15], case reports [5][6][7] or case series [16,18]. Though the pathophysiology of this disease is not well understood, it is suggested that head and neck amyloidosis is linked to the light chain subtype (AL) [15,16].…”

Section: Introductionmentioning

confidence: 99%

Disseminated Amyloidosis in Head and Neck - Literature Review and Discussion of an Unusual Case

Farias¹

2016

GJO

View full text Add to dashboard Cite

Primary amyloidosis of head and neck is an extremely rare event and there are few cases reported in the literature. Amyloidosis is a group of diseases that have as etiology the extracellular proteins deposition in many organs, causing architectural and functional damage to them. This article´s objective is to report a case of primary amyloidosis localized in skin, tongue, parotid and upper airways simultaneously in one patient and do a literature review on the topic. Patient W.K.Y. 72 years-old, from China, living in Brazil for 6 months, come out with vesicles in the head and neck about one year ago. The disease had been spreading to face and neck skin as well as lips, oral mucosa and tongue. Because of oral feeding impairment and dyspnoea, the patient was taken to an emergency service, where clinical investigation started. As previous treatment, It was reported the use of Chinese medicine, acupuncture and herbs. Patient had no diabetes, hypertension, Alzheimer's disease or nephropathy. Also, he had no family history of any degenerative or infectious disease. Patient diagnosis was: primary amyloidosis with secondary rheumatoid component. For treatment, a prednisolone pulse therapy associated with colchicine was elected, causing regression edema of tongue, suprahyoid region, lips and parotid glands, likewise about 50% of skin neck vesicles disappeared Head and neck Amyloidosis occurs in 19% of cases and may affect the skin, ear, nasal cavity, oral cavity, parotid, pharynx and larynx. Larynx is the most commonly affected organ in this region, accounting for the largest number of case reports and case series in the literature, with treatment and well-established management. The diagnosis is made based on histopathologycal examination and biochemical characterization of amyloid type. The treatment is based on the surgical resection with variable recurrence rates, according to affected organ.

show abstract