Treatment of Refractory Persistent Corneal Epithelial Defects: A Standardized Approach Using Continuous Wear PROSE Therapy

Abstract

Continuous wear of a PROSE device, using a strictly standardized regimen, constitutes an effective, safe treatment option for refractory persistent epithelial defects.

What Makes a Scleral Lens Fit Physiological? A Case Report

“…Cressey et al, demonstrated resolution of vascularized limbal keratitis similar to the appearance of the present case [18]. Resolution of recalcitrant persistent epithelial defects have also been observed with PROSE treatment suggesting that there is a beneficial and therapeutic effect conferred onto the ocular surface with PROSE devices or scleral lenses [19][20][21].…”

The treatment of ocular hypotony after trabeculectomy with a scleral lens: A case series

“…Ciralsky et al have described a scleral lens care regime for extended wear in compromised corneas; daily removal, cleaning and reinsertion with replacement of the reservoir fluid with an antibiotic drop [30]. In this case series the scleral lenses are worn on eyes without severe ocular surface disease and none developed infectious keratitis.…”

Morselized Amniotic Membrane Tissue for Refractory Corneal Epithelial Defects in Cicatricial Ocular Surface Diseases

“… 1 As shown herein, conservative treatments such as topical lubricants, autologous serum, bandage contact lens, and tarsorraphy failed to treat these corneal epithelial defects. Although refractory cases can be benefited by scleral contact lens, 29 its use was limited in patients as illustrated in this study due to the presence of significant symblepharon. Similarly, placement of PROKERA could not be instituted due to symblepharon in three of four patients.…”