Treatment of SCN4A‐induced myotonic crisis

Abstract

be comprised of different items. Although it would be theoretically possible to co-calibrate and equate the two versions, the risk remains of these FSS scores being treated as directly equivalent.Finally and given the above caveats, we propose as an alternative that existing and more contemporary PROs that measure the impact on hand use in daily activities be chosen based on the strongest evidence for content and construct validity, thus complementing the symptom severity scale. For example, in a recent trial on sensory relearning after surgery for CTS, we used three subscales of the Michigan Hand Questionnaire (MHQ) that showed statistically significant improvements in unilateral and bilateral hand activities. 7 A further advantage is that the MHQ generates separate scores for the left and right hands, which is particularly important because CTS can have a unilateral or bilateral presentation.

Reply to: Revisiting the Functional Status Scale of the Boston Carpal Tunnel Questionnaire, a comment concerning the use of digital communication technology

“…For example, in a recent trial on sensory relearning after surgery for CTS, we used three subscales of the Michigan Hand Questionnaire (MHQ) that showed statistically significant improvements in unilateral and bilateral hand activities. 7 A further advantage is that the MHQ generates separate scores for the left and right hands, which is particularly important because CTS can have a unilateral or bilateral presentation.…”