Treatment of Subglottic Carcinoma

The effectiveness of intra-arterial chemoradiotherapy （IACRT） against advanced laryngeal cancer has recently been reported. Yet, the indication of IACRT in cases with neck lymph node metastasis has not been discussed. Although planned neck dissection after radiotherapy is performed at many institutions, the radiotherapy often cause unfavorable postoperative complications. We treated a 57 -year-old male, whose chief complaint was hoarseness, at our university hospital. Fiberoptic examination revealed an irregular tumor on the right subglottic lesion extending to the right ventricle. Images from computed tomography suggested the presence of metastatic cervical lymph nodes. Subglottic squamous cell carcinoma of the larynx （T 2 N 2 bM 0 ） was histologically diagnosed. As a treatment, selective neck dissection for the cervical metastasis was first performed. During surgery, the supra-and inferior-thyroidal arteries were preserved. Ten days after the surgery, IACRT for the local tumor was given every other week using the supra-thyroidal artery. The IACRT was continued for five weeks and, as a result, the tumor has completely disappeared. The patient has been free from recurrence for more than a year.

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Advanced Laryngeal Cancer Treated by Intra-arterial Chemoradiotherapy after Neck Dissection: A Case Report

Mihashi

Chitose

Maeda

et al. 2010

LARYNX JAPAN

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Four Cases of Primary Subglottic Cancer : Investigation of the Specific Development

et al. 2018

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Primary subglottic cancer is a very rare condition. In almost cases, a delayed diagnosis of subglottic cancer is made in patients complaining of hoarseness or dyspnea. This often leads to a poor prognosis. The subglottic tumor spreads to invade deep structures, including the muscles or interstitial tissue. We reported four cases of subglottic cancer that were observed from 1986 to 2008. This number constitutes 1.0% of all the laryngeal cancers that were observed during this period. Three cases were treated with total laryngectomy with neck dissection. The remaining case was treated with radiotherapy alone. The overall five-year-survival rate was 75%. In two cases, horizontal serial pathological sections showed tumor invasion to thyro-arythenoid muscle (Case 1) and invasion of the thyroid cartilage across the anterior commissure of the larynx (Case 2). We stressed the necessity of total laryngectomy with hemi-thyroidectomy and unilateral neck dissection including dissection of the paratracheal lymph node, as the treatment for subglottic cancer according to the characterization of its pattern of spread. Keywords： subglottic cancer, treatment, tendency for spread

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Treatment of Subglottic Carcinoma

Cited by 2 publications

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Advanced Laryngeal Cancer Treated by Intra-arterial Chemoradiotherapy after Neck Dissection: A Case Report

Advanced Laryngeal Cancer Treated by Intra-arterial Chemoradiotherapy after Neck Dissection: A Case Report

Four Cases of Primary Subglottic Cancer : Investigation of the Specific Development

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