This study was carried out to evaluate laparoscopic retroperitoneal ureterolithotomy (RPUL) as a viable option to open surgical ureterolithotomy, laparoscopic transperitoneal ureterolithotomy (TPUL) & endoscopic urology and to assess its place in the spectrum of alternatives for the surgical treatment of ureteric calculi in a tertiary care centre. This study was conducted on 20 selected patients of single large impacted calculus of size more than 8mm in upper & middle ureter. It was observed that excessive bleeding was present in only one (5%) of the patients, while need for conversion to open ureterolithotomy was seen in 8 (40%) cases. No major peri-operative complications were encountered. From our experience, it can be concluded that this procedure has definitely shown decreased post-operative discomfort, decreased requirement of post-operative analgesia, better cosmesis, early return to work and less morbidity. RPUL can be considered as another well-established armamentarium in the armour of laparoscopic surgeons and is recommended as an effective minimally invasive primary treatment in large, impacted difficult stones in the upper & mid ureter.