Treatment Outcomes and Survival of Patients with Gastric Cancer in Hamadan, Iran: A Retrospective Study

Abstract

This study aimed to evaluate the effect of various factors and treatments protocols' outcomes on the survival of patients with gastric cancer (GC). In a retrospective cohort study Patients with a definite diagnosis of GC who had been hospitalized at the Mahdie Hospital of Hamadan, Iran, from 2005-2017 were investigated. GC-related survival for different factors, types, locations of the tumor, sites of metastasis, and used treatment methods investigated. Data analyze performed by SPSS software version 21. 95 patients, including 66 (71%) male, and 27 (29%) female, were identified. The mean age was 63.88±12.41 years. The largest proportion of tumors was located in the cardia (29.7%), body (18.9%), and antrum (18.9%) of the stomach. The most common site of metastasis was the liver (52.6%), and lung (26.3%). The average survival of patients was 40.64±4.58 months, and the one, two, three, four, and five years' survival of investigated patients were 0.68, 0.49, 0.43, 0.39, and 0.34 years, respectively. The average survival of patients with and without metastasis were 16.35±3.27 and 46.97±5.30 months (P=0.004). The Pearson correlation coefficient between the survival and total dose of RT, total number of CT sessions, and dose of each RT session were -0.003 (P-value=0.98), 0.006 (P-value=0.97), and -0.108 (P-value=0.412), respectively. Results show that there were no statistically significant differences between the average survival of patients and used treatment method, grade, type of cancer, and CT medicine. But survival of patients with metastasis was significantly lower than patients without metastasis (P=0.029).

The Effect of LRP-1 Gene and Mir-205 on Cardiovascular Disease in Iraqi Patients with Familial Hypercholesterolemia

“…2). A non-template control (NTC), non-amplification control (NAC), and nonprimer control (NPC) were included as negative controls for each reaction in duplicate [22].The expression ratio was calculated without a calibrator sample 2-ΔCt according to the following:…”

Impact of Vitamin D Elements and Osteoporosis Factors in Postmenopausal Iraqi Women with T2DM

“…Data showing a reduction in bone turnover were discovered when biomarkers of bone turnover were investigated, particularly in wellcontrolled diabetes persons. This furthermore explains the existing phenomenon in T2DM patients of delayed bone loss [46,47]. In a study of T2DM patients, Wakasugi and colleagues [48,49] found that a substantial decline in BMD occurred only after the twentieth year of the illness, demonstrating the delayed bone loss pattern reported in T2DM patients.…”