Treatment regimens used in the management of Helicobacter pylori in Colombia

Valladales‐Restrepo, Luis Fernando; Correa-Sánchez, Yessenia; Aristizábal-Carmona, Brayan Stiven; Machado‐Alba, Jorge Enrique

doi:10.1016/j.bjid.2022.102331

Cited by 6 publications

(3 citation statements)

References 26 publications

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“…From those papers that created open datasets, 12 of those datasets were created for specific Latin American countries. 5 datasets were created for Colombia: 1 with social determinants of health and nutrition data for Public Health tasks [ 21 ], and 4 with a more clinical point of view which are a muscle dysmorphia dataset [ 22 ], body fat measurement [ 23 ], endoscopic ultrasound scans [ 24 ], and a treatment of Helicobacter pylori dataset [ 25 ]. 8 datasets were created for Brazil: 2 from a Public Health perspective which are BASICS [ 26 ] with epidemiologic data, and the dataset on child vaccination [ 27 ]; 1 dataset of laboratory exams [ 28 ]; 1 dataset of images of leprosy called AI4Leprosy [ 29 ]; 1 open dataset with electronic health records called ORBDA [ 30 ]; 2 datasets for genomics [ 31 , 32 ]; and one trial with the effects of BCG vaccination for COVID-19 to [ 33 ].…”

Section: Resultsmentioning

confidence: 99%

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A scoping review of the landscape of health-related open datasets in Latin America

Restrepo,

Quion,

Vásquez-Venegas

et al. 2023

PLOS Digit Health

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Artificial intelligence (AI) algorithms have the potential to revolutionize healthcare, but their successful translation into clinical practice has been limited. One crucial factor is the data used to train these algorithms, which must be representative of the population. However, most healthcare databases are derived from high-income countries, leading to non-representative models and potentially exacerbating health inequities. This review focuses on the landscape of health-related open datasets in Latin America, aiming to identify existing datasets, examine data-sharing frameworks, techniques, platforms, and formats, and identify best practices in Latin America. The review found 61 datasets from 23 countries, with the DATASUS dataset from Brazil contributing to the majority of articles. The analysis revealed a dearth of datasets created by the authors themselves, indicating a reliance on existing open datasets. The findings underscore the importance of promoting open data in Latin America. We provide recommendations for enhancing data sharing in the region.

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Section: Resultsmentioning

confidence: 99%

“…Of the total datasets in Latin America, only 7 (5%) require credentialing. Three of these correspond to databases created in research papers ( Table 2 ): SELAdb database [ 31 , 32 ], the Helicobacter pylori dataset [ 25 ], and the Cuban Human Brain Mapping Project (CHBMP) [ 42 ].…”

Section: Resultsmentioning

confidence: 99%

A scoping review of the landscape of health-related open datasets in Latin America

Restrepo,

Quion,

Vásquez-Venegas

et al. 2023

PLOS Digit Health

View full text Add to dashboard Cite

show abstract

“…Reports from general practice showed that 20% of practitioners used a single antibiotic, and 2.6% did not use PPIs. The authors concluded that the management of H. pylori infection is heterogenous and inconsistent with the current recommendations [ 110 ]. This is similar to the conclusions drawn by the analysis of Hp-EuReg data based on 21,533 patients monitored for 5 years [ 11 ], leaving much room for education and improvement in the future [ 12 ].…”

Section: Eradication Of the Infection In Regions With A High ...mentioning

confidence: 99%

Newer, Older, and Alternative Agents for the Eradication of Helicobacter pylori Infection: A Narrative Review

Buzás¹,

Birinyi

2023

Antibiotics

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Although discovered 40 years ago, Helicobacter pylori infection is still raising diagnostic and therapeutic problems today. The infection is currently managed based on statements in several guidelines, but implementing them in practice is a long process. Increasing antibiotic resistance and weak compliance of the patients limit the efficacy of eradication regimens, leaving much room for improvement. Third-generation proton pump inhibitors have added little to the results of the first two generations. Potassium-competitive acid blockers have a stronger and longer inhibitory action of acid secretion, increasing the intragastric pH. They obtained superior results in eradication when compared to proton pump inhibitors. Instead of innovative antibiotics, derivatives of existing antimicrobials were developed; some new fluoroquinolones and nitazoxanide seem promising in practice, but they are not recommended by the guidelines. Carbonic anhydrase inhibitors have both anti-secretory and bactericidal effects, and some researchers are expecting their revival in the treatment of infection. Capsules containing components of the eradication regimens have obtained excellent results, but are of limited availability. Probiotics, if containing bacteria with anti-Helicobacter pylori activity, may be useful, increasing the rates of eradication and lowering the prevalence and severity of the side effects.

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Innovative Self Nano‐Emulsifying Drug Delivery Systems for Peptic Ulcer Therapy: A Review

Mujtaba,

Arshad,

Aman

et al. 2024

Part & Part Syst Charact

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Peptic ulcer disease (PUD) adversely affects ≈4 million individuals globally and remains pervasive among 5–10% of the general population. Mucosal lesions prompted by the ulceration lead to the penetration through mucosal layers, ultimately resulting in cavity formation and inflammation. Conventional therapeutic modalities for peptic ulcers have shown unfavorable effects, relapses, and numerous drug interactions. The genesis of gastric ulcers is catalyzed via an imbalanced interplay between environmental lesions, defensive mechanisms, and the restoration of gastric mucosa. Lipid based nanotechnology involved in self‐nanoemulsifying drug delivery system (SNEDDS) is being tremendously involved in opening avenues in innovative pharmaceutical delivery systems in terms of improving solubility and regenerative healing against peptic ulcers. Biological macromolecules can be incorporated into SNEDDS to embellish the drug delivery system on an advanced level. Herein, in this review, the potential of SNEDDS as a viable carrier for administering biomacromolecules for regenerative healing in ulcers is discussed in detail.

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Treatment regimens used in the management of Helicobacter pylori in Colombia

Cited by 6 publications

References 26 publications

A scoping review of the landscape of health-related open datasets in Latin America

A scoping review of the landscape of health-related open datasets in Latin America

Newer, Older, and Alternative Agents for the Eradication of Helicobacter pylori Infection: A Narrative Review

Innovative Self Nano‐Emulsifying Drug Delivery Systems for Peptic Ulcer Therapy: A Review

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