Treatment-Related Complications in Children Hospitalized With Disseminated Lyme Disease

Abstract

We describe here treatment approaches and treatment-related complications in 138 hospitalized children with disseminated Lyme disease. The patients who received parenteral antibiotics had a higher rate of complications than those who received oral therapy (15.4 vs 4.2 per 1000 days of therapy, respectively; P < .05). Oral therapy should be used preferentially if either route is supported by current guidelines.

Descriptive Data on Trends Among Patients Hospitalized With Lyme Disease in Southwest Michigan, 2017–2021

“…Estimates of carditis rates among US Lyme inpatients are between 5% and 11% [ 5 , 8 , 9 ]. A single-center pediatric study [ 8 ] in Pennsylvania identified Lyme meningitis in 38% of pediatric patients hospitalized for Lyme disease from 2007 to 2014; I am not aware of similar data in US adults. In general, Lyme hospitalizations in the United States appear to be increasing [ 5 ].…”