Treatment Results by Uneven Fractionated Irradiation, Low-Dose Rate Telecobalt Therapy as a Boost, and Intraoperative Irradiation for Malignant Glioma.

Yamada, Satoshi; Takai, Yoshihiro; Nemoto, Kenji; Ogawa, Yoshihiro; Kakuto, Yoshihisa; Hoshi, Akihiko; Sakamoto, Kiyohiko; Kayama, Takamasa; Yoshimoto, Takashi

doi:10.1620/tjem.167.259

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Intraoperative Radiotherapy: Targeting Infiltrative Margins1

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2023

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Cited by 4 publications

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“…Intraoperative radiosurgery also allowed higher dose delivery to the surgical bed [87]. In this context, Japanese scientists conducted the first studies indicating a benefit of using intraoperative radiotherapy in patients with malignant gliomas in the early 1990s (Table 5) [79][80][81]. At that time, IORT was mainly delivered by means of electron-based intraoperative radiotherapy (IOERT), which has several technical limitations, including inadequate electron cone sizes, inadequate low energies, and areas of insufficient target volume coverage [77].…”

Section: Intraoperative Radiotherapy: Targeting Infiltrative Marginsmentioning

confidence: 99%

Surgical Treatment of Glioblastoma: State-of-the-Art and Future Trends

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Beck

Schnell

et al. 2022

JCM

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Glioblastoma (GBM) is a highly aggressive disease and is associated with poor prognosis despite treatment advances in recent years. Surgical resection of tumor remains the main therapeutic option when approaching these patients, especially when combined with adjuvant radiochemotherapy. In the present study, we conducted a comprehensive literature review on the state-of-the-art and future trends of the surgical treatment of GBM, emphasizing topics that have been the object of recent study.

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