The research discussed in this article was conducted to investigate and document the performance of conventional sodium-form strong-acid resins for the combined removal of barium, radium, and hardness under controlled conditions. The reasons for the study were: (1) the premature leakage of barium from strong-acid ion exchange columns, (2) a lack of controlled laboratory studies to determine the factors affecting resin performance, and (3) a lack of documentation regarding the effect of the quantity of regenerant applied on effluent quality and on effluent quality as a function of the amount of water processed during a run.