Treatment wish of individuals with known and unknown restless legs syndrome in the community

Happe, Svenja; Vennemann, Mechtild; Evers, Stefan; Berger, Klaus

doi:10.1007/s00415-008-0922-7

Cited by 64 publications

(41 citation statements)

References 12 publications

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“…Single nucleotide polymorphisms (SNPs) of the MC1R gene are associated with a fair skin phenotype, and these SNPs are overrepresented in areas of high latitude where their presence has been favored by low ultraviolet burden to maintain the ultraviolet-induced synthesis of vitamin D. 55,56 In general, low RLS prevalence is seen in southern countries: Greece, Turkey, Spain, Portugal, and Italy 4,31-36 ; high prevalence is seen in northern countries: Norway, Sweden, Iceland, and Finland 8,45-51 ; and moderate prevalence is seen in central countries: England, Serbia, Germany, northern Italy, Netherlands, France, and Denmark. 4,35,[37][38][39][40][41][42][43][44]47 Fig. 1 shows a map of Europe, where prevalence is reported per 1000 persons and has been standardized so that prevalence of men and women were averaged (if reported separately), as in a previous publication.…”

Section: Europementioning

confidence: 99%

Restless Leg Syndrome Across the Globe

Koo

2015

Sleep Medicine Clinics

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Section: Europementioning

confidence: 99%

Restless Leg Syndrome Across the Globe

Koo

2015

Sleep Medicine Clinics

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“…The Dortmund Health Study (DHS) [18] was conducted in the city of Dortmund in the western part of Germany. For examinations and interviews, a random sample from the respective population register, stratified by age and gender, was drawn.…”

Section: Methodsmentioning

confidence: 99%

Restless legs syndrome and cancer: an analysis in three independent studies

Fuhs¹,

Bentama²,

Hoffmann³

et al. 2014

Epidemiol Rep

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We report results from three independently conducted studies on the prevalence of cancer in restless legs syndrome (RLS) cases and non RLS cases. Already in 1955 Ekbom observed RLS in patients with subsequently detected cancer. Since then only three case reports and one article assessed the relationship between RLS and cancer patients undergoing chemotherapy. The observed proportion of RLS in these cancer patients (18.3%) was about twice as high as in general population studies. Two of our studies were general population based studies (Dortmund Health Study (DHS); Study of Health in Pomerania (SHIP)) and one was performed among members of the German and Swiss RLS patient organizations (Course of Restless Legs Syndrome-Study (COR-S)). Additionally we used data from the population based, regional cancer registry of the Muenster district for comparisons. Our data show that in all three studies the prevalence of cancer was higher in RLS cases than in non cases for both genders. In two of the studies the increased risk was in part explained by age. The data of the COR-Study revealed a statistically significant higher risk for cancer in RLS subjects compared to the population based data of the regional cancer registry of Muenster. Our results suggest a higher proportion of cancer among RLS cases compared to individuals without RLS. Given an RLS prevalence of about 5 to 10 percent in the general population, a need to rule out cancer in patients with a new onset of RLS, especially among the elderly patients is important.

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“…Epidemiologische Untersuchungen der letzten Jahre zeigen, dass das Restless-LegsSyndrom (RLS) mit einer Lebenszeitprä-valenz von 7-10% vorkommt [4]. Schät-zungsweise hat etwa 1-3% der Bevölke-rung klinisch relevante Symptome [2,11]. Damit dürfte das RLS eine der häufigs-ten Ursachen von Beinschmerzen, insbesondere der nächtlichen Beinschmerzen, sein.…”

Section: Isolierte Beinschmerzen Sind Ein Häufiges Jedoch Im Vergleiunclassified

Restless-Legs-Syndrom und nächtliche Beinschmerzen

Hornyak

Stiasny-Kolster²,

Evers³

et al. 2011

Schmerz

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Pain in the legs belongs to the five most frequent regional pain symptoms. Restless legs syndrome (RLS) presents a particular differential diagnosis for pain in the legs, which is characterized by a nocturnal urge to move the legs often associated with painful sensations in the legs. It is one of the most common neurological disorders and probably the leading cause of nocturnal pain in the legs. In this overview, the diagnosis and therapy of RLS as well as aspects of pain therapy of the disorder are presented. In addition, the differential diagnoses for exclusion of other specific causes of nocturnal pain in the legs are discussed.

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Treatment wish of individuals with known and unknown restless legs syndrome in the community

Cited by 64 publications

References 12 publications

Restless Leg Syndrome Across the Globe

Restless Leg Syndrome Across the Globe

Restless legs syndrome and cancer: an analysis in three independent studies

Restless-Legs-Syndrom und nächtliche Beinschmerzen

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