Treatment with a topical glucocorticoid, budesonide, reduced the variability of rhinomanometric nasal airway resistance

Abstract

The variability of nasal airway resistance was significantly reduced by treatment with topical budesonide for 6 out of 8 healthy volunteers participating in an unblinded repeated 5 month trial where the participants served as their own controls.

Measurements of nasal airflow and patency: a critical review with emphasis on the use of peak nasal inspiratory flow in daily practice

“…Rhinomanometry can be used for the evaluation of the symptoms of anatomical and/or mucosal nasal obstruction , research in nasal physiology, allergen and aspirin challenge testing , pre‐ and post‐treatment assessments of surgical or medical therapy , evaluation of adenoid hypertrophy in children and evaluation of patients with sleep apnoea . Patient selection for septal and turbinate surgery is largely undertaken around the world without any objective confirmation of genuine mechanical obstruction .…”

“…AR can be used to measure reduced nasal patency in patients with anatomical problems , rhinitis, and to measure the effect of challenges and treatment effects …”

Paradoxical increase in nasal airway resistance after topical nasal decongestion – does it really exist? A retro‐ and prospective study

“…However, our technique of using topical nasal decongestant twice and waiting 15 min before rhinomanometry is carried out has shown to be more effective than exercise on bicycle . If there is suspicion of oedema, a combination of topical nasal decongestants with other drugs such as nasal steroids may be necessary for maximum decongestion . We had no such suspicion among our 36 patients.…”