Treatment with buckwheat bran extract prevents the elevation of serum triglyceride levels and fatty liver in KK-A&lt;sup&gt;y &lt;/sup&gt;mice.

Hosaka, Toshio; Sasaga, Sayaka; Yamasaka, Yukiko; Nii, Yoshitaka; Edazawa, Kazuhiro; Tsutsumi, Rie; Shuto, Emi; Okahisa, Naoki; Iwata, S.; Tomotake, Hiroyuki; Sakai, Tohru

doi:10.2152/jmi.61.345

Cited by 15 publications

(8 citation statements)

References 33 publications

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“…At the same time, the protein in buckwheat is gluten-free, and it will process buckwheat and its products as an alternative nutritious food to substitute the gluten grains without causing allergens and digestive issues [3,4]. Subsequently, buckwheat contains rare bioactive components such as rutin, quercetin, vitexin, anthocyanidins, and myo-inositol, which play an important role in anti-oxidation metabolism of the human body as scavengers of active oxygen and possess healing effects on some chronic diseases like diabetes [5], fatty liver [6], and even cancer [7]. Additionally, it is should be noticed that buckwheat is the only pseudocereal rich in natural rutin, which process buckwheat became a beneficial source of dietary rutin [2].…”

Section: Introductionmentioning

confidence: 99%

psbE-psbL and ndhA Intron, the Promising Plastid DNA Barcode of Fagopyrum

Huang

Wang

et al. 2019

IJMS

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Buckwheat is an important functional food material with high nutritional value. However, it is still a difficult task for the taxonomy studies of wild buckwheat that are only based on morphology. In order to demonstrate the most efficient DNA barcode in the phylogenetic research of buckwheat, promote the investigation of wild buckwheat, and also reveal the phylogenetic relationship between Fagopyrum species, psbE-psbL and ndhA intron were validated here, which previously have been proved to be promising DNA barcode candidates for phylogenetic studies in genera Fagopyrum. Meanwhile, ndhA intron + psbE-psbL and matK + psbE-psbL could distinguish the relationship between species clearly. Combining the results of morphology and molecular markers, we suggested the buckwheat species should be divided into two subgroups, one subgroup consisted of F. tataricum, F. esculentum, F. cymosum and its related wild species, and the other subgroup included other wild buckwheat species. Our results could fulfill molecular markers of taxonomy research in genera Fagopyrum, promote wild buckwheat species identification, and assist in the use of wild buckwheat resources in the future. Additionally, the phylogenetic relationship revealed here could provide valuable information for molecular breeding of buckwheat and provide reference for inter-species hybridization.

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Section: Introductionmentioning

confidence: 99%

psbE-psbL and ndhA Intron, the Promising Plastid DNA Barcode of Fagopyrum

Huang

Wang

et al. 2019

IJMS

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“…Hosaka et al examined the lipid‐lowering effect of buckwheat bran extract (BBE) in diabetic mice. KK‐Ay mice that received 6‐week treatment with BBE showed decreased body weight and liver weight compared to control (vehicle) mice, but there was no significant difference in food intake. BBE treatment prevents liver triglyceride accumulation and decreases serum triglyceride levels.…”

Section: Other Buckwheat Productsmentioning

confidence: 89%

Hypolipidemic activity of common (Fagopyrum esculentum Moench) and tartary (Fagopyrum tataricum Gaertn.) buckwheat

2014

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Buckwheat grain has well-balanced nutritional value, whereas its digestibility is relatively low. This review summarizes recent advances in studies on the hypolipidemic activity of buckwheat. The most remarkable function is a powerful hypocholesterolemic activity of buckwheat protein in rats, which is far stronger than that of soy protein. The cholesterol-lowering effect is mediated by mechanisms involving higher excretion of fecal sterols and lower digestibility of buckwheat protein. The insoluble fraction of buckwheat protein associates with cholesterol and reduces micelle cholesterol uptake in caco-2 cells. Furthermore, consumption of buckwheat protein suppresses cholesterol-induced gallstones and body fat in rodents. Buckwheat sprouts also have hypolipidemic activity in rats or type 2 diabetic mice. Tartary buckwheat bran extract reduced the serum level of total cholesterol and triglyceride in hyperlipidemic rats. The consumption of buckwheat seed reduced low-density lipoprotein cholesterol in the pastureland Mongolian population. Taken together, buckwheat may be beneficial for prevention of hyperlipidemia.

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“…Buckwheat is characterized by high protein content with balanced amino acid composition, high content of minerals (e.g., magnesium, zinc and iron) and other biologically active phytochemicals (such as rutin) as well as dietary fiber [ 3 ]. It was observed that buckwheat consumption had a positive effect on the lipid profile—lowering the levels of total cholesterol, triglycerides and low-density lipoproteins and increasing the levels of high-density lipoproteins [ 4 ]. Consequently, the risk of occurrence of type 2 diabetes mellitus, cancer and cardiovascular disease was reduced [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

Gluten-Free Cereals and Pseudocereals as a Potential Source of Exposure to Toxic Elements among Polish Residents

et al. 2022

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Background: Nutritional food quality plays a crucial role in maintaining human health. However, food and drinking water, along with occupational exposure, are the main routes of exposure to toxic elements for humans. The main aim of this study was to determine the content of As, Cd, Pb and Hg in naturally gluten-free grains and products made from buckwheat, millet, maize, quinoa and oat. The safety of consumption of the products tested was also assessed. Methods: The contents of As, Cd and Pb were determined using inductively coupled plasma mass spectrometry (ICP-MS). To measure Hg, an atomic absorption spectrometry method (AAS) with the amalgamation technique was applied. To assess the level of consumption of the tested products, an online survey was conducted. To estimate health risk, three indicators were used: the target hazard quotient (THQ), cancer risk (CR) and hazard index (HI). The research material obtained 242 different samples without replications. Results: The highest average content of As, Cd, Pb and Hg were observed for the following groups of products: oat (10.19 µg/kg), buckwheat (48.35 µg/kg), millet (74.52 µg/kg) and buckwheat (1.37 µg/kg), respectively. For six samples, exceedance of established limits was found—three in the case of Cd and three of Pb. Due to the lack of established limits, As and Hg content of the tested products was not compared. Generally, no increased health risks were identified. Conclusions: Based on the obtained results, the consumption of gluten-free cereals and pseudocereals available on the Polish market seems to be safe. However, there is a great need to establish maximum levels of the toxic elements, especially As and Hg in cereal products in European legislation.

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Treatment with buckwheat bran extract prevents the elevation of serum triglyceride levels and fatty liver in KK-A<sup>y </sup>mice.

Cited by 15 publications

References 33 publications

psbE-psbL and ndhA Intron, the Promising Plastid DNA Barcode of Fagopyrum

psbE-psbL and ndhA Intron, the Promising Plastid DNA Barcode of Fagopyrum

Hypolipidemic activity of common (Fagopyrum esculentum Moench) and tartary (Fagopyrum tataricum Gaertn.) buckwheat

Gluten-Free Cereals and Pseudocereals as a Potential Source of Exposure to Toxic Elements among Polish Residents

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