2021
DOI: 10.1016/j.injury.2021.01.016
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Treatments, cost and healthcare utilization of patients with segmental bone defects

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Cited by 20 publications
(16 citation statements)
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“…The complexity of managing large bone defects is welldescribed in the literature, as well as the various methods of treatment [2,3], and their results. [30][31][32] However, evidence on the health economic aspect of their effective management is extremely scarce [33]. Theoretically, a complete health economic analysis includes direct, indirect, and intangible costs [4], whereas a cost effectiveness study should address both the societal and the health-care payer perspectives evaluating all relevant costs and benefits to the patient over their lifetime [34,35].…”
Section: Discussionmentioning
confidence: 99%
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“…The complexity of managing large bone defects is welldescribed in the literature, as well as the various methods of treatment [2,3], and their results. [30][31][32] However, evidence on the health economic aspect of their effective management is extremely scarce [33]. Theoretically, a complete health economic analysis includes direct, indirect, and intangible costs [4], whereas a cost effectiveness study should address both the societal and the health-care payer perspectives evaluating all relevant costs and benefits to the patient over their lifetime [34,35].…”
Section: Discussionmentioning
confidence: 99%
“…Theoretically, a complete health economic analysis includes direct, indirect, and intangible costs [4], whereas a cost effectiveness study should address both the societal and the health-care payer perspectives evaluating all relevant costs and benefits to the patient over their lifetime [34,35]. Recently, Norris et al [33] published a database analysis utilizing two different US-based sources including 904 patients with either the diagnosis of fracture/nonunion/ osteomyelitis, treated with bone graft, cement spacer, or a frame fixator. Payer costs were analysed from the index admission to 12 months postoperatively.…”
Section: Discussionmentioning
confidence: 99%
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“…These types of bone defects occur in a number of settings, including acute trauma, fracture nonunion, osteomyelitis, neoplasia, spine pseudarthrosis, and revision total joint arthroplasty [ 3 ]. The associated healthcare costs for segmental bone defects are estimated as high as $300,000 per case, with significant associated patient morbidity [ 8 ].…”
Section: Introductionmentioning
confidence: 99%
“…are unable to heal by themselves [1]. Thus, their reconstruction remains a challenge for clinicians and has a high economical and societal cost [2]. Currently, autologous bone graft is the gold standard solution to treat such defects, but it is associated with some drawbacks such as limited availability, increase in the number of surgeries required, significant postoperative donor-site morbidity, and inconsistency of repair in large bone defects exceeding typically about 5 cm 3 [3,4].…”
Section: Introductionmentioning
confidence: 99%