Treatments for gestational diabetes

Abstract

Analysis 1.12. Comparison 1 Any specific treatment versus routine antenatal care (subgroups by type of specific treatment), Outcome 12 Birthweight > 90th centile.

Lifestyle interventions for the treatment of women with gestational diabetes

“…We acknowledge the valuable contributions of Nisreen Alwan, Jane West and Derek Tuffnell who were the authors of the original review (Alwan 2009). …”

“…The original review (Alwan 2009) has been split into three new reviews due to the complexity of the included interventions. The following new review protocols are underway.…”

Stillbirths: what difference can we make and at what cost?

“…Complications range from variations in birthweight to fetal malformations and potentially excess perinatal mortality. Reduction in perinatal mortality is associated with any specifi c treatment for gestational diabetes versus routine antenatal care, 25 and with care of maternal diabetes before conception versus no care 9 (table 1). Moreover, intensive management of gestational diabetes (including specialised dietary advice, increased monitoring, and tailored dietary therapy) versus conventional management (dietary advice and insulin as needed) is associated with a reduction in the risk of stillbirth (table 1).…”

A comparative study of metformin and glyburide in gestational diabetes mellitus

“…9 Historically, insulin therapy has been the first line pharmacological treatment in GDM, but recently oral agents, especially metformin and glyburide, have been under investigation. 10 The need of searching scope of oral hypoglycemic agents in management of gestational diabetes is because insulin treatment is expensive, needs frequent monitoring, requires refrigerated storage, skilled handling, is to be taken in divided doses and therefore may not be popular with poor and illiterate women in low resource countries. Good patient compliance to treatment with these hypoglycemic agents, as well as their low-cost, calls for their increased use in low resource countries.…”