A B S T R AC T : Idiopathic head tremor (IHT) syn-drome is a recognized but poorly characterized movement disorder in English bulldogs (EBs). The data analyzed were collected via a detailed online questionnaire and video recordings. Thirty-eight percent of the population demonstrated IHT. The first presentation was early in life. There was no sex or neutered status predisposition. The condition disappeared with time in 50% of the cases. The direction of the head movement was vertical or horizontal. The number of episodes per day and the duration of the episodes were greatly variable. The majority of episodes occurred at rest. Most of the episodes were unpredictable. And there was no alteration of the mental status for most dogs during the episodes. Stress has been reported as a suspected trigger factor. IHT in EBs can be considered an idiopathic paroxysmal movement disorder. 2 A recent study in Doberman pinschers characterized IHT as a sudden onset of vertical and/or horizontal rhythmic head movements lasting from a few seconds to several hours.1 However, there remains a lack of data about this condition in other dog breeds. The aim of the current study was to phenotypically characterize IHT in the EB to identify potential risk factors and to compare this breed-specific canine disorder with similar canine and human movement disorders.
Materials and MethodsThis study was approved by the Ethics and Welfare Committee of the Royal Veterinary College, University of London, England (approval number URN 201100039H). EB owners and breeders were contacted and invited to complete a detailed questionnaire available online and to provide video recordings of the episodes and pedigree information of their dogs. Some owners were contacted by e-mail or telephone for data verification. This questionnaire was designed by the primary author and a board-certified veterinary neurologist (H.A.V.). Video recordings of the episodes were also requested and analyzed by reviewing the events in slow motion. It was decided that each responder could enter only 1 affected dog. The Mann-Whitney U test or Fisher's exact test was used to compare groups. A P < 0.05 was considered statistically significant.
Results
Study PopulationTwo hundred thirty-four EB owners participated in the study. Eighty-nine EBs had reported episodes of
191IHT and were considered the affected patient population. This group consisted of 41 male (54%; 95% CI, 44%-64%) and 48 female (46%; 95% CI, 36%-56%) dogs between 5 months and 12 years of age (median, 4 years) and weighing between 12 and 40 kg (median, 26 kg). Forty-one of the 89 dogs (46%; 95% CI, 36%-56%) were neutered, whereas 48 (54%; 95% CI, 44%-64%) were sexually intact animals. The remaining 145 dogs had not demonstrated signs suggestive of IHT at the time of the questionnaire and served as the control group for the affected animal population. This last group consisted of 62 females (43%; 95% CI, 35%-51%) and 83 males (57%; 95% CI, 49%-65%). Eighty-four dogs (58%; 95% CI, 55%-66%) were sexually intact, and 61 (...