Trend Analysis of Superoxide Dismutase 3 (SOD3) and Reactive Oxygen Species (ROS) levels on BioSmart and Safe Bus Passengers

Asri, A R Hairul; Prasetyo, Awal; Sadhana, Udadi; Antari, Arlita Leniseptaria; Rahajeng, Hehera

doi:10.17485/ijst/v14i34.769

Cited by 1 publication

(1 citation statement)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Rapid regeneration of IL-6 may contribute to host defense during tissue injury and pathogen infection, while over-synthesis and large accumulation of IL-6 can lead to pathology disease [17]. Therefore, it can be said that IL-6 has a dual role in the on-off system in controlling inflammation [18].…”

Section: Discussionmentioning

confidence: 99%

The Immunoglobulin A and Interleukin-6 Levels of “Biosmart and Safe Bus” and Regular Bus Passengers

Syifa¹,

Prasetyo²,

Sadhana³

et al. 2023

Proceedings of the 1st International Conference for Health Research – BRIN (ICHR 2022)

Self Cite

View full text Add to dashboard Cite

The inhalant increasing risk of transmission in public transportation, is buses. Biosmart and safe bus apply the principle that the bus compartment which is a biological environment must be in a balanced state according to the disease triangle concept that is influenced by the host, in this case is the passenger, the agent causing the infection is a virus and the environment is the room in the bus cabin. The aim of the present study is to analyze the differences in IgA and IL-6 levels of Biosmart and safe bus passengers and regular bus passengers. This research is a non-blinded randomized control trial with pre-posttest design. Seventy passengers were randomly separated into two groups. Control group (n = 35) uses regular bus, and intervention group uses Biosmart and safe bus (n = 35). Nasal wash was taken by ENT specialists, and the levels of Sinonasal IgA and IL-6 were interpreted by ELISA. The data were analyzed by using Mann Whitney, Wilcoxon, Independent t-test and Paired t-test. The results is sinonasal IgA level got significant increase in all groups, respectively on pretest-posttest of intervention group 17,89 ± 30,19 (p = 0,021), control group 30,18 ± 76,09 (p = 0,014) while the delta IgA level on control group and intervention group resulted in no significant difference (p = 0,182). The IL-6 level also increased in all groups with significant difference (p = 0.000), the delta resulted in significant difference (p = 0,013) with intervention group 13,38 ± 0,96 and control group 13,90 ± 1,27. Interleukin-6 sinonasal levels of Regular Bus and Biosmart and Safe Bus passengers show difference with higher

show abstract

Section: Discussionmentioning

confidence: 99%