Trend of type 1 diabetes incidence in children between 2009 and 2019 in Elazig, Turkey

Abstract

Objective: To assess the incidence of T1D in children aged <15 years in Elazig, Turkey.Method: The data of children who have been registered as child with T1D in the database of pediatric diabetes clinic was analyzed. Childhood census data were acquired from the Turkish Statistical Institute. The incidence rates of T1D were calculated for the whole group as well as separately for age group, gender, year of diagnosis, and place of residence, viz. either urban or rural per 100 000 persons per year.The change of incidence during the 10 year observation period was analyzed. Results:The overall mean incidence of T1D in study period was 16.7/100 000 [95% confidence interval (CI): 14.6-19.0] persons per year. The incidence rates of T1D varied from 10.2 to 24.1/100 000 persons per year, representing 2.4-fold variation between 2009 and 2019. The lowest incidence rate was in children aged 0 to 4 years (9.6/100 000 persons per year; CI: 6.9-12.9). There was no difference in incidence rate between genders, incidence rates was significant higher in urban residents. A significant increasing trend of T1D was detected in the total 10-year observation period; the average annual percent change was 7.8%. Subgroup analysis showed that there was significant increasing trend in boys, urban residents, and children aged 5 to 9 years groups.Conclusion: This study demonstrated increase in T1D incidence of in children in Elazig and highest regional incidence rate of T1D until now in Turkey compared to previous limited data.

Change in the Frequency of Diabetic Ketoacidosis in Children with Newly Diagnosed Type 1 Diabetes in the Central Anatolia Region of Turkey over the Years Before and After the Coronavirus Disease 2019 Pandemic: A Single-Center Experience

“… 24 In a study examining the years 2009 to 2019 in Elazığ, it was observed that the increasing trend in the incidence of T1D was especially in boys, urban residents, and children between the ages of 5 and 9 years. 25 In another study examining newly diagnosed T1D cases in Elazığ between 2016 and 2019, it was observed that the presence of DKA at the time of diagnosis was associated with high HbA1c levels, and that presentation with severe DKA was associated with people living in rural areas and low education levels of mothers. 26 Newly diagnosed T1D cases examined in tertiary care in the Southern region of Turkey between 2019 and 2021 were compared as 2 groups before and after the pandemic, and it was found that the frequency of severe DKA was higher in cases diagnosed after the pandemic, and antibody positivity for celiac disease and glutamic acid decarboxylase were observed more common.…”

Trends in incidence rates of childhood type 1 diabetes mellitus: A retrospective study in Isfahan province, Iran

“…The reported incidence rate in Turkey was higher than in the present study. This might be due to the studied age group 23 . We included children aged <20 years, and the rate in children aged 15–19 years is lower than children aged 5–15 years.…”

“…In the present study, the mean age of diagnosis was 9.89 years, which was higher than that reported in the study of Esen et al . in Turkey 23 .…”

Overview of diabetes and its curative approach using medicinal plants: A narrative review

“…It is predicted that by 2030, this figure would rise to 578 million, or 10.2% of the adult population worldwide, and that by 2045, it will reach 700 million, or 10.9% of the adult population worldwide. The estimated prevalence of diabetes in men and women worldwide in 2019 is 9.6% and 9.0%, respectively, for the total population of each gender (Esen and Okdemir, 2020). Additionally, an estimated 4.2 million adults aged 20 to 99 died from diabetes-related complications in 2019, and the cost of treating diabetes-related health issues is anticipated to be at least 760 billion USD, or 10% of all spending on adults (Banday et al, 2020).…”