Trends and disparities in disease burden of age-related macular degeneration from 1990 to 2019: Results from the global burden of disease study 2019

Jiang, Bo; Jiang, Chun; Li, Jianqing; Lu, Peirong

doi:10.3389/fpubh.2023.1138428

Cited by 11 publications

(4 citation statements)

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“…Notably, in response to VISION 2020, high-income regions allocated funding for diverse programs aimed at reducing rates of low vision and blindness. The adoption of more proactive diagnostics, early detection, and treatment strategies could potentially bolster the performance of high-income regions [ 27 ]. Addressing this phenomenon warrants increased attention and further investigations into the mechanisms underlying these disparities.…”

Section: Discussionmentioning

confidence: 99%

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Changing Trends in the Global Burden of Cataract Over the Past 30 Years: Retrospective Data Analysis of the Global Burden of Disease Study 2019

Jiang,

Wu,

Liu

et al. 2023

JMIR Public Health Surveill

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Background Cataracts now account for the largest proportion of the global burden of blindness and vision loss. Understanding the changing trends in the global burden of cataracts over the past 30 years and the next 15 years is of clear significance for the prevention and control of cataracts in key populations. As far as we know, research on the future burden of cataracts is lacking. Objective This study aims to assess the global burden of cataracts over the past 30 years by using age-period-cohort modeling and to estimate trends in the next 15 years. Methods Data were obtained from the Global Burden of Disease Study 2019, the United Nations Development Programme, and the WHO (World Health Organization) Global Health Observatory data repository. The assessment of trends and disparities in the number and rate of disability-adjusted life years (DALYs) for cataracts from 1990 to 2019 was conducted. The association between the age-standardized DALY rate (ASDR) and the socio-demographic index (SDI), human development index (HDI), national levels of particulate matter <2.5 μm in diameter (PM2.5), and ambient ultraviolet radiation (UVR) was determined using linear regression analysis. Additionally, we used the Nordpred (Harald Fekjær and Bjørn Møller) age-period-cohort model to predict the cataract burden from 2020 to 2034. Results Globally, the number of DALYs due to cataract increased from 3,492,604 (95% uncertainty interval [UI] 2,481,846-4,719,629) in 1990 to 6,676,281 (95% UI 4,761,210-9,006,193) in 2019. The ASDRs due to cataract decreased from 93.17 (95% UI 66.14-125.32) in 1990 to 82.94 (95% UI 59.06-111.75) in 2019, with an average annual percentage change of –0.37 (95% CI –0.44 to –0.3; P<.001). Age, female sex, air pollution, smoking, high fasting plasma glucose levels, and a high body mass index were risk factors for the burden of cataracts. SDI and HDI were negatively correlated with ASDRs of cataracts, while PM2.5 and UVR were positively associated with them. Higher DALY rates were also associated with lower SDI (R2=0.1939; P<.001), lower HDI (R2=0.2828; P<.001), national PM2.5 concentration (R2=0.1874; P<.001), and ambient UVR levels (R2=0.2354; P<.001). The prediction model suggested that the number of DALYs due to cataract will continue to rise globally, while the cataract DALY rate will continue to decrease. Conclusions While the ASDR of cataracts has decreased, there has been a notable increase in the number of DALYs over the past 30 years. Projections suggest that the global burden of cataracts will continue to rise over the next 15 years. To address this challenge, appropriate prevention and treatment policies must be implemented.

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Section: Discussionmentioning

confidence: 99%

“…The adoption of more proactive diagnostics, early detection, and treatment strategies could potentially bolster the performance of high-income regions [27]. Addressing this phenomenon warrants increased attention and further investigations into the mechanisms underlying these disparities.…”

Section: Principal Findingsmentioning

confidence: 99%

Changing Trends in the Global Burden of Cataract Over the Past 30 Years: Retrospective Data Analysis of the Global Burden of Disease Study 2019

Jiang,

Wu,

Liu

et al. 2023

JMIR Public Health Surveill

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“…The Disease Modelling-Meta Regression version 2.1 was used to model the epidemiological outcomes of IOFBs in children and adolescents, which is a Bayesian meta-regression framework widely employed in GBD epidemiological modelling [ 8 , 9 ]. Data regarding all children and adolescents with IOFBs in GBD 2019 were included.…”

Section: Methodsmentioning

confidence: 99%

Global, regional, and national burdens of intraocular foreign bodies in children and adolescents from 1990 to 2019: a trend analysis

Ren,

Jiang,

Liu

et al. 2023

BMC Public Health

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Background This study aimed to evaluate trends in global, regional, and national burdens of intraocular foreign bodies among children and adolescents (aged 0 − 19 years) between 1990 and 2019 according to age, sex, and socio-demographic index. Methods This study obtained data from the Global Burden of Disease Study 2019 and evaluated the number of cases, rates per 100,000 persons, and average annual percentage changes among children and adolescents. The annual percentage changes in the incidence and years lived with disability rates across various age groups were investigated using joinpoint software. Results For intraocular foreign bodies in children and adolescents, the incidence and year lived with disability rates decreased in all age groups between 1990 and 2019. However, the number of incident cases and years lived with disability increased from 1091.94 [95% uncertainty interval (UI), 610.91–1839.52] and 89,245 (95% UI, 6.65–18.67) in 1990 to 1134.85 (95% UI, 665.01–1867.50) and 92,108 (95% UI, 32,052–192,153) in 2019, respectively. Age was positively correlated with the number of cases, incidence, and years lived with disability rates. However, there were significant decreases in both the incidence and years lived with disability rates among children and adolescents, especially in the 15–18 years age group, males, and most high-income regions. Notably, the incidence and years lived with disability rates were significantly decreased in middle and high-middle socio-demographic index regions but were increased in low and low-middle socio-demographic index regions. Conclusions Despite the remarkable progress between 1990 and 2019 in reducing the global burden of intraocular foreign bodies, there has been an increase in the number of cases, with substantial disparity across age groups, sexes, regions, and countries. Our results could inform more effective strategies for reducing the burden among children and adolescents.

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“…Age-related macular degeneration (AMD) is another critical issue characterized by the loss of central vision and significantly hampering daily activities like reading and facial recognition. Its prevalence is estimated at 7.7 million people worldwide [ 2 ]. Glaucoma, encompassing a group of conditions that damage the optic nerve, often due to high intraocular pressure, poses a severe risk of vision loss and blindness if left untreated.…”

Section: Introductionmentioning

confidence: 99%

VisionaryVR: An Optical Simulation Tool for Evaluating and Optimizing Vision Correction Solutions in Virtual Reality

Hosp,

Dechant,

Sauer

et al. 2024

Sensors

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In the rapidly advancing field of vision science, traditional research approaches struggle to accurately simulate and evaluate vision correction methods, leading to time-consuming evaluations with limited scope and flexibility. To overcome these challenges, we introduce ‘VisionaryVR’, a virtual reality (VR) simulation framework designed to enhance optical simulation fidelity and broaden experimental capabilities. VisionaryVR leverages a versatile VR environment to support dynamic vision tasks and integrates comprehensive eye-tracking functionality. Its experiment manager’s scene-loading feature fosters a scalable and flexible research platform. Preliminary validation through an empirical study has demonstrated VisionaryVR’s effectiveness in replicating a wide range of visual impairments and providing a robust platform for evaluating vision correction solutions. Key findings indicate a significant improvement in evaluating vision correction methods and user experience, underscoring VisionaryVR’s potential to transform vision science research by bridging the gap between theoretical concepts and their practical applications. This validation underscores VisionaryVR’s contribution to overcoming traditional methodological limitations and establishing a foundational framework for research innovation in vision science.

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Trends and disparities in disease burden of age-related macular degeneration from 1990 to 2019: Results from the global burden of disease study 2019

Cited by 11 publications

References 48 publications

Changing Trends in the Global Burden of Cataract Over the Past 30 Years: Retrospective Data Analysis of the Global Burden of Disease Study 2019

Changing Trends in the Global Burden of Cataract Over the Past 30 Years: Retrospective Data Analysis of the Global Burden of Disease Study 2019

Global, regional, and national burdens of intraocular foreign bodies in children and adolescents from 1990 to 2019: a trend analysis

VisionaryVR: An Optical Simulation Tool for Evaluating and Optimizing Vision Correction Solutions in Virtual Reality

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