2019
DOI: 10.14338/ijpt-19-00051.1
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Trends and Disparities of Proton Therapy Use among Patients with Head and Neck Cancer: Analysis from the National Cancer Database (2005-14)

Abstract: Purpose: The purpose of this study was to analyze national trends and disparities in proton therapy use among patients with head and neck cancer receiving radiotherapy to primary disease sites. Patients and Methods: Using the National Cancer Database, we identified patients diagnosed with any nonmetastatic head and neck primary malignancy between 2005 and 2014 who were treated with radiation therapy or proton therapy directed… Show more

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Cited by 12 publications
(13 citation statements)
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“…In a study analyzing the National Cancer Database of patients treated with PBT, patients who are treated in an academic setting ( p < 0.001) and in the highest median household income quartile (>$63,000, p = 0.002) were more likely to receive PBT. These findings suggest that patients from more affluent backgrounds are more likely to receive PBT 65 . This trend is noteworthy to recognize early to ensure the inclusion of economically disadvantaged patients in future studies.…”
Section: Limitationsmentioning
confidence: 78%
See 1 more Smart Citation
“…In a study analyzing the National Cancer Database of patients treated with PBT, patients who are treated in an academic setting ( p < 0.001) and in the highest median household income quartile (>$63,000, p = 0.002) were more likely to receive PBT. These findings suggest that patients from more affluent backgrounds are more likely to receive PBT 65 . This trend is noteworthy to recognize early to ensure the inclusion of economically disadvantaged patients in future studies.…”
Section: Limitationsmentioning
confidence: 78%
“…These findings suggest that patients from more affluent backgrounds are more likely to receive PBT. 65 This trend is noteworthy to recognize early to ensure the inclusion of economically disadvantaged patients in future studies. These patients are necessary to acquire an accurate representation of both the beneficial outcomes and the toxicities.…”
Section: Limitationsmentioning
confidence: 99%
“…The lack of long-term follow-up is due, in part, to the contemporary nature of PBT technology along with the limited regional access resulting in fewer patients and shorter follow-up time available [ 43 ]. Late toxicities such as chronic dysphagia can be challenging to capture given the extended time to develop and/or progress symptoms as well as its association with baseline function [ 44 ].…”
Section: Discussionmentioning
confidence: 99%
“… 1 , 2 Black patients are less likely to receive any RT, 3 including use of advanced technologies. 4 , 5 , 6 Previous studies investigating disparities in receipt of PBT evaluated only a single cancer site, 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 age group, 16 or geographic region 17 and, importantly, only included patients receiving RT rather than all patients for whom RT is recommended. Because Black patients are less likely than White patients to receive any type of RT, 3 , 6 , 18 , 19 , 20 , 21 , 22 , 23 , 24 these studies 7 , 10 , 11 , 12 , 13 , 16 , 25 , 26 , 27 , 28 , 29 , 30 might have underestimated the racial disparity in receipt of PBT.…”
Section: Introductionmentioning
confidence: 99%