Trends and Resource Utilization in Kawasaki Disease Hospitalizations in the United States, 2008–2017

Vasudeva, Rhythm; Poku, Frank Adusei; Thommana, Mary; Parmar, Garima; Umscheid, Jacob; Parmar, Narendrasinh; Koranteng, Comfort A; Singh, Aastha; Patel, Kamlesh; Yagnik, Priyank; Donda, Keyur; Bhatt, Parth; Dapaah‐Siakwan, Fredrick

doi:10.1542/hpeds.2021-006142

Cited by 4 publications

(1 citation statement)

References 38 publications

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“…A retrospective cross-sectional study carried out in the US utilized hospitalization data with ICD-10 diagnostic codes for KD between 2008 and 2017 [21]. Consistent with other studies, they reported that children <5 years had the highest hospitalization rates (16.2 per 100 000 children).…”

Section: Kawasaki Diseasesupporting

confidence: 60%

Epidemiology of systemic vasculitis

Ozguler,

Esatoglu,

Hatemi

2023

Current Opinion in Rheumatology

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Purpose of review Epidemiology of vasculitides exhibit geographic variation and data from some parts of the world are still scarce. Increased recognition of these rare diseases and improvement in diagnosis and patient care may lead to changes in their epidemiology. In this review, we aimed to highlight the most recent work on the epidemiology of systemic vasculitis. Recent findings New data from countries where information on the epidemiology of giant cell arteritis, Takayasu arteritis and Behçet syndrome were limited have revealed that these conditions are not as rare as previously believed. The incidence rates during the coronavirus disease 2019 pandemic highlight the link between Kawasaki disease and respiratory pathogens. The use of different classification criteria hampers the comparison of true incidence and prevalence rates in antineutophil cytoplasmic antibody (ANCA)-associated vasculitis and its subtypes between geographies and over time. Summary Recent studies have highlighted the epidemiology of vasculitides in different parts of the world and changing trends. Standardization of study design and disease definitions is needed to improve the reliability and comparability of the results.

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Section: Kawasaki Diseasesupporting

confidence: 60%

Epidemiology of systemic vasculitis

Ozguler,

Esatoglu,

Hatemi

2023

Current Opinion in Rheumatology

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Comparison of Risk-Scoring Systems in Predicting Kawasaki Disease Associated Coronary Artery Dilation in a North American Cohort

Schwartzenburg,

Strelow,

Chowdhury

2024

Pediatr Cardiol

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Scoring systems used to predict morbidity in children with Kawasaki disease (KD) have been developed and validated in Asian populations. The objective of this study was to assess their utility in predicting the development of coronary artery dilation in children with KD in North America. This was a secondary analysis of a National Institutes of Health / National Heart, Lung, and Blood Institute (NIH/NHLBI) Pediatric Heart Network public use dataset from a multicenter, randomized controlled trial of pulse steroid therapy in KD in a North American cohort. The primary outcome of interest was development of coronary artery dilation. The Harada, Kobayashi, Egami, and Sano scoring systems, originally developed to predict risk of intravenous immunoglobulin (IVIG) resistance in Kawasaki patients in Japan, were applied to this cohort. Subjects were kept in the analysis only if there were complete data for every element of each scoring system—Harada (n = 132), Kobayashi (n = 88), Egami (n = 139), and Sano (n = 82). Patients classified as high-risk by the Harada score were more likely to have significant coronary artery dilation (p = 0.042), were more likely to require IVIG retreatment (p = 0.002), and were more likely to require hospital readmission (p < 0.001). The Egami, Kobayashi, and Sano scores were not predictive for any measured outcome. The Harada score can be useful in identifying KD patients at risk for developing coronary artery dilation and IVIG resistance. The Harada score has demonstrated higher sensitivity but lower specificity, making it a valuable screening tool that may benefit from supplementary diagnostic methods.

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An Update on Kawasaki Disease

Goel,

Yalcindag

2024

Curr Rheumatol Rep

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Trends and Resource Utilization in Kawasaki Disease Hospitalizations in the United States, 2008–2017

Cited by 4 publications

References 38 publications

Epidemiology of systemic vasculitis

Epidemiology of systemic vasculitis

Comparison of Risk-Scoring Systems in Predicting Kawasaki Disease Associated Coronary Artery Dilation in a North American Cohort

An Update on Kawasaki Disease

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