Trends in Acute Kidney Injury and Outcomes After Early Percutaneous Coronary Intervention in Patients ≥75 Years of Age With Acute Myocardial Infarction

Khera, Sahil; Kolte, Dhaval; Aronow, Wilbert S.; Palaniswamy, Chandrasekar; Mujib, Marjan; Ahmed, Ali; Chugh, Savneek; Balasubramaniyam, Nivas; Edupuganti, Malik; Frishman, William H.; Fonarow, Gregg C.

doi:10.1016/j.amjcard.2013.06.008

Cited by 26 publications

(31 citation statements)

References 18 publications

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“…Our results are in agreement with earlier reports demonstrating increasing incidences of AKI with time (6,8,15,16). Our study can be most readily compared to the study by Bagshaw SM et al (6), which examined the incidence and outcomes of AKI in all ICU admissions using ANZICS APD.…”

Section: Discussionsupporting

confidence: 92%

Acute Kidney Injury Requiring Dialysis in Severe Sepsis

Sakhuja

Kumar

Gupta

et al. 2015

Am J Respir Crit Care Med

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Section: Discussionsupporting

confidence: 92%

Acute Kidney Injury Requiring Dialysis in Severe Sepsis

Sakhuja

Kumar

Gupta

et al. 2015

Am J Respir Crit Care Med

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“…Epidemiological investigations indicate that AKI and AKI‐D incidence is increasing among hospitalized patients . Using the NIS, Hsu found that the odds of developing AKI‐D increased by 10% annually among hospitalized patients in the United States between 2000 and 2009 .…”

Section: Discussionmentioning

confidence: 99%

“…Using the NIS, Hsu found that the odds of developing AKI‐D increased by 10% annually among hospitalized patients in the United States between 2000 and 2009 . Similarly, Lenihan and Khera utilized the NIS to investigate the temporal incidence of AKI and AKI‐D, but among cardiac surgery and elderly PCI patients . Compared to 1999, the adjusted odds of AKI and AKI‐D in 2008 for cardiac surgery patients were 3.30 and 2.23, respectively .…”

Section: Discussionmentioning

confidence: 99%

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Incidence and In‐Hospital Mortality of Acute Kidney Injury (AKI) and Dialysis‐Requiring AKI (AKI‐D) After Cardiac Catheterization in the National Inpatient Sample

Brown

Rezaee

Nichols

et al. 2016

JAHA

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“…[35–38] Though the increase in administrative coding likely accounts for some of the increase in AKI, other investigations that have used creatinine-based definitions for AKI have also suggested a temporal increase in the incidence of AKI. [39] Other studies have also demonstrated that mortality due AKI-D has decreased in the U.S.[23, 27, 43] Khera and colleagues noted an adjusted odds of 0.74 of mortality among elderly patients undergoing angioplasty who developed AKI-D in 2010 compared to 2002, which translated into a 26% reduction in mortality for patients with AKI-D.[43]…”

Section: Discussionmentioning

confidence: 99%

Reduced Mortality Associated with Acute Kidney Injury Requiring Dialysis in the United States

Brown¹,

Rezaee

Hisey

et al. 2016

Am J Nephrol

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Background: Dialysis-requiring acute kidney injury (AKI-D) is a documented complication of hospitalization and procedures. Temporal incidence of AKI-D and related hospital mortality in the US population has not been recently characterized. We describe the epidemiology of AKI-D as well as associated in-hospital mortality in the US. Methods: Retrospective cohort of a national discharge data (n = 86,949,550) from the Healthcare Cost and Utilization Project's National Inpatient Sample, 2001-2011 of patients' hospitalization with AKI-D. Primary outcomes were AKI-D and in-hospital mortality. We determined the annual incidence rate of AKI-D in the US from 2001 to 2011. We estimated ORs for AKI-D and in-hospital mortality for each successive year compared to 2001 using multiple logistic regression models, adjusted for patient and hospital characteristics, and stratified the analyses by sex and age. We also calculated population-attributable risk of in-hospital mortality associated with AKI-D. Results: The adjusted odds of AKI-D increased by a factor of 1.03 (95% CI 1.02-1.04) each year. The number of AKI-D-related (19,886-34,195) in-hospital deaths increased almost 2-fold, although in-hospital mortality associated with AKI-D (28.0-19.7%) declined significantly from 2001 to 2011. Over the same period, the adjusted odds of mortality for AKI-D patients were 0.60 (95% CI 0.56-0.67). Population-attributable risk of mortality associated with AKI-D increased (2.1-4.2%) over the study period. Conclusions: The incidence rate of AKI-D has increased considerably in the US since 2001. However, in-hospital mortality associated with AKI-D hospital admissions has decreased significantly.

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Trends in Acute Kidney Injury and Outcomes After Early Percutaneous Coronary Intervention in Patients ≥75 Years of Age With Acute Myocardial Infarction

Cited by 26 publications

References 18 publications

Acute Kidney Injury Requiring Dialysis in Severe Sepsis

Acute Kidney Injury Requiring Dialysis in Severe Sepsis

Incidence and In‐Hospital Mortality of Acute Kidney Injury (AKI) and Dialysis‐Requiring AKI (AKI‐D) After Cardiac Catheterization in the National Inpatient Sample

Reduced Mortality Associated with Acute Kidney Injury Requiring Dialysis in the United States

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