Trends in aging and skin care: Ayurvedic concepts

Datta, Hema Sharma; Paramesh, Rangesh

doi:10.4103/0975-9476.65081

Cited by 62 publications

(34 citation statements)

References 5 publications

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“…Centella asiatica (L.) Urban (Apiaceae), commonly known as Gotu Kola, is widely used in folk medicine to treat a wide range of illness. This is a very useful herb described in Ayurveda as an anti-aging plant (Datta & Paramesh, 2010). Phytochemical studies on different parts of C. asiatica reveal the presence of pentacyclic triterpenes asiatic acid and madecassic acid and their respective glycosides, namely, asiaticoside (a trisaccharide moiety is linked to the aglycone unit of asiatic acid) and madecassoside (a trisaccharide moiety is linked to the aglycone unit of madecassic acid).…”

Section: Introductionmentioning

confidence: 99%

Matrix metalloproteinase, hyaluronidase and elastase inhibitory potential of standardized extract ofCentella asiatica

Nema

Maity

Sarkar

et al. 2013

Pharmaceutical Biology

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Context: Centella asiatica (L.) Urban (Apiaceae), a valuable herb described in Ayurveda, is used in the indigenous system of medicine as a tonic to treat skin diseases. Objective: Centella asiatica methanol extract and its ethyl acetate, n-butanol and aqueous fraction, were subjected for the evaluation of skin care potential through the in vitro hyaluronidase, elastase and matrix metalloproteinase-1 (MMP-1) inhibitory assay. Materials and methods: The C. asiatica plant was extracted with methanol and fractionated with ethyl acetate, n-butanol and water. The enzymatic activities were evaluated using ursolic acid and oleanolic acid as standards. Isolate molecule asiaticoside was quantified in the crude extract and fractions through high-performance liquid chromatography (HPLC) and structural was characterized by liquid chromatography-mass spectroscopy (LC-MS) and 1 H nuclear magnetic resonance (NMR). Isolated compound was also evaluated for in vitro enzyme assays. Results: Extract exhibited anti-hyaluronidase and anti-elastase activity with IC 50 of 19.27 AE 0.37 and 14.54 AE 0.39 mg/mL, respectively, as compared to ursolic acid. Centella asiatica n-butanol fraction (CAnB) and isolated compound showed significant hyaluronidase (IC 50 ¼ 27.00 AE 0.43 and 18.63 AE 0.33 mg/mL) and elastase (IC 50 ¼ 29.15 AE 0.31 and 19.45 AE 0.25 mg/mL) inhibitory activities, respectively, and also showed significant MMP-1 inhibition (p50.05 and p50.01). Discussion and conclusion: n-Butanol fraction was found to be most effective among the all fractions from which asiaticoside was isolated and further quantified by HPLC. This work concludes that the asiaticoside from C. asiatica may be a prospective agent for skin care.

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Section: Introductionmentioning

confidence: 99%

Matrix metalloproteinase, hyaluronidase and elastase inhibitory potential of standardized extract ofCentella asiatica

Nema

Maity

Sarkar

et al. 2013

Pharmaceutical Biology

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“…36 Although, A. vera was described in Nigeria as useful in the treatment of skin diseases facial cleansers and body cream. 37,38 As far back as 3500 BCE, the use of A. vera was very ancient in times of an Egyptian. 39 In Ayurveda medicine, A. vera is known as the treatment for skin diseases.…”

Section: Correlation Between Climatic Characteristics Of the Study Armentioning

confidence: 99%

Contemporary Use of Phytocosmetics in Three Districts from North-Eastern Algeria

Bouzabata¹

2017

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Background:In Algeria, the cosmetic market is competitive, with an annual growth of 12%. Because of the toxicity of synthetics cosmetics, the industry is currently more concentrated on herbal cosmetics. Phytocosmetic is an important aspect of traditional medicine in Algerian culture, whose information is scanty. Objective: The present study has been conducted to assess quantitatively the use of herbs in phytocosmetics application. Method: Data was collected from 300 users via face to face interviews using semi-structured questionnaire in three districts from North-eastern Algeria: Annaba, El Tarf and Skikda. Five parameters were evaluated including the demographic characteristics, the form of cosmetic preparation and, medicinal stories used in cosmetic applications. Results: The soap (67%) and a fixed oil (56%) were the preparation forms most used in phytocosmetics applications. Although, five medicinal plants were recorded: Aloe vera (L.) Burm.F., Matricaria recutita L., Lavandula angustifolia Mill., Citrus limon (L.) Osbeck and Ricinus communis L. The highest relative citation frequency (RFC) was attributed to A. vera in the three district Skikda (0.68), Annaba (0.57), and El Tarf (0.43). Eleven traditional recipes have been described. Conclusion: This study is able to record the available information the importance of phytocosmetic in traditional medicine. However, further research should be conducted in Algeria, to explore the toxicity of these products.

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“…Growing concern over side effects of chemical-based products is the main reason behind this trend. The Ayurvedic natural cosmetics business of India is growing at the rate of 15-20% per year-much higher than India's overall cosmetics business that has a growth rate of 7-8% [4].…”

Section: Introductionmentioning

confidence: 99%