The impact of AI on Industry 4.0 is discussed in this chapter, with a focus on how it works best with IoT to create autonomous factories. It is emphasized how important AI is for predictive maintenance, downtime reduction, and utilizing ML and deep learning for increased productivity. This study looks at how NLP and machine vision may revolutionize document processing and work in tandem with intelligent document processing to remove administrative bottlenecks. In addition to technical details, the chapter explores wider ramifications, including proactive field service and customized solutions. Supply chain optimization, cost reduction, and value extraction from datasets all depend on the integration of AI and data analytics. Designed with experts and policymakers in mind, this succinct story offers insightful information about AI's contribution to the evolution of manufacturing to a global audience ready to understand the rapid changes taking place.