Trends in der Prävalenz von Demenz und Parkinson – Eine Analyse auf Basis aller gesetzlich versicherten Personen im Alter 65+in Deutschland zwischen 2009 und 2012

Nerius, Michael; Ziegler, Uta; Doblhammer, Gabriele; Fink, Anne

doi:10.1055/a-0829-6494

Cited by 14 publications

(14 citation statements)

References 47 publications

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“…By 2050 their share will rise to nearly 13% [ 9 ]. In Germany, the prevalence of dementia in 65-69-year-olds is 1.3%, rising to 22.8% for 85-89-year-old people [ 10 ]. There are currently about 1.7 million people living with dementia in Germany.…”

Section: Introductionmentioning

confidence: 99%

Attitudes of legal guardians and legally supervised persons with and without previous research experience towards participation in research projects: A quantitative cross-sectional study

et al. 2021

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Background Vulnerable groups, e.g. persons with mental illness, neurological deficits or dementia, are often excluded as participants from research projects because obtaining informed consent can be difficult and tedious. This may have the consequence that vulnerable groups benefit less from medical progress. Vulnerable persons are often supported by a legal guardian in one or more demands of their daily life. We examined the attitudes of legal guardians and legally supervised persons towards medical research and the conditions and motivations to participate in studies. Methods We conducted a cross-sectional study with standardized surveys of legal guardians and legally supervised persons. Two separate questionnaires were developed for the legal guardians and the supervised persons to asses previous experiences with research projects and the reasons for participation or non-participation. The legal guardians were recruited through various guardianship organizations. The supervised persons were recruited through their legal guardian and from a previous study among psychiatric patients. The data were analysed descriptively. Results Alltogether, 82 legal guardians and 20 legally supervised persons could be recruited. Thereof 13 legal guardians (15.6%) and 13 legally supervised persons (65.0%) had previous experience with research projects. The majority of the guardians with experience in research projects had consented the participation of their supervised persons (n = 12 guardians, 60.0%; in total n = 16 approvals). The possible burden on the participating person was given as the most frequent reason not to participate both by the guardians (n = 44, 54.4%) and by the supervised persons (n = 3, 30.0%). The most frequent motivation to provide consent to participate in a research study was the desire to help other patients by gaining new scientific knowledge (guardians: n = 125, 78.1%; supervised persons: n = 10, 66.6%). Conclusions Overall, an open attitude towards medical research can be observed both among legal guardians and supervised persons. Perceived risks and no sense recognized in the study are reasons for not participating in medical research projects.

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Section: Introductionmentioning

confidence: 99%

Attitudes of legal guardians and legally supervised persons with and without previous research experience towards participation in research projects: A quantitative cross-sectional study

et al. 2021

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“…Darüber hinaus werden vielfältige einflussnehmende Umgebungsfaktoren beschrieben. Dazu gehören insbesondere Änderungen des Lebensstils [14,21] Dieses Dokument wurde zum persönlichen Gebrauch heruntergeladen. Vervielfältigung nur mit Zustimmung des Verlages.…”

Section: Diskussionunclassified

“…Tönges et al 8 berichten für eine deutsche Stichprobe von 1,5 Millionen Krankenhaus-Patienten eine Fallzahlzuname im Zeitraum 2010 bis 2015 von 29,6% bei Fällen mit geringgradiger Beeinträchtigung (ICD-10: G20.00) und 85% für Patienten mit Wirkungsfluktuationen (ICD-10: G20.01). Demgegenüber wurde für eine ambulante deutsche Stichprobe für einen Vierjahreszeitraum von 2009 bis 2012 jedoch eine sinkende Prävalenz bei Frauen bei einer gleichbleibenden Prävalenz bei Männern festgestellt 14 . Auch international gibt es Hinweise auf eine gleichbleibende oder sinkende Inzidenz durch Studien aus UK 15 , Taiwan 16 und den Niederlanden 17 .…”

Section: Diskussionunclassified

Zeitliche Veränderung der Prävalenz von Parkinson-Diagnosen in Deutschen Hausarzt- und Neurologischen Praxen von 2010 bis 2019

Bohlken¹,

Riedel‐Heller

Kramer

et al. 2022

Fortschr Neurol Psychiatr

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Zusammenfassung Hintergrund Bis 2040 wird mit einer erheblichen Prävalenzzunahme der Parkinson-Erkrankung und damit einhergehend mit einer erheblichen Belastung der Versorgungssysteme gerechnet. Ziel der Studie war es deshalb, eine Veränderung der Anzahl an Parkinson-Patienten bereits im Zeitraum 2010 bis 2019 in deutschen Haus- und neurologischen Facharztpraxen zu untersuchen. Methode Die vorliegende Querschnittstudie basiert auf den Daten von 411 Hausarzt- (HA) und 56 neurologischen Facharzt-Praxen (FA) aus der IQVIA Disease Analyzer Datenbank. Die Anzahl der etablierten und neu diagnostizierten Patienten mit Parkinson-Erkrankung wurde in den Jahren 2010 und 2019 mit Alters- und Geschlechtsstruktur und der Anteil therapierten Patienten untersucht.Ergebnisse Die Zahl der Parkinson-Patienten veränderte sich geringfügig zwischen 2010 bis 2019 von 3352 (0,36% aller Patienten) auf 3541 (0,33%) in den HA-Praxen und von 4976 (3,48%) auf 4826 (3,34%) in den FA-Praxen. Die Anzahl der neu diagnostizierten Fälle fiel bei den HA-Praxen leicht von 862 (0,09% aller Patienten) auf 836 (0,08%) und bei den FA-Praxen von 1818 (1,27%) auf 1372 (0,95% aller Patienten). Der Anteil an Frauen unter allen Parkinson-Erkrankten sank sowohl in HA- und FA- Praxen von 52,0% bzw. 50,2% auf 47,3% bzw. 46,0%. Das Durchschnittsalter stieg bei den HA-Praxen von 77,1 (SD 10,4) im Jahr 2010 auf 77,7 (SD 9,3) Jahre im Jahr 2019 und in FA-Praxen von 74,6 (SD 9,9) auf 75,8 (SD 9,9) Jahre. Diskussion Die prognostizierte Zunahme von Parkinson-Patienten in der ambulanten Versorgung lässt sich für den Zeitraum 2010 bis 2019 nicht bestätigen. Es gab jedoch eine Verschiebung der Altersstruktur zu höheren Altersgruppen und eine Verringerung des Anteils an Frauen mit einer Parkinson-Erkrankung. Neben ätiologischen Erklärungen sollten Besonderheiten des Versorgungssystems und methodische Limitationen berücksichtigt werden.

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“…Globally, the number of people that are affected will increase from 6.1 million people in 2016 to 9.3 million people in 2030 [ 2 , 3 ]. The number of PD patients is also rising in Germany [ 4 ]. The disease brings immense costs to the German health care system [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of an individualized, tablet-based physiotherapy training programme for patients with Parkinson’s disease: the ParkProTrain study, a quasi-randomised controlled trial

et al. 2022

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Background Regular physical activity is of great relevance in Parkinson's disease (PD). It is part of the inpatient multimodal Parkinson's complex treatment (MKP) in Germany. However, there is often a lack of human resources in outpatient settings to continue an interprofessional approach. A large proportion of PD patients live a predominantly sedentary lifestyle and do not get enough exercise. Methods The intervention group (IG) used a tablet-based physiotherapy training programme at home for a period of nine months. We conducted a quasi-randomised longitudinal study with three measurement times (at the beginning (t0) and end of MKP (t1) and at 9 months after MKP (t2)). The primary outcome measured was PD-specific quality of life using the PDQ-8. The secondary outcome focused on participation restrictions, falling anxiety, sleep disorder, anxiety and depression as well as comorbidity, pain, performance capability and physical activity. Results For n = 93 IG and n = 137 control group (CG) patients, evaluable cases were available for all measurement times. Both groups achieved significant improvements in all parameters at the end of MKP. These parameters deteriorated again at nine months after MKP for most parameters and were even below the baseline levels. However, this deterioration was less pronounced in the IG than in the CG. For general health and social participation, a significant slightly positive effect was observed in the IG nine months after MKP when compared with the baseline level. Paying attention to physical activity slightly increased in the IG for the catamnesis survey compared to baseline. Nearly all IG patients were satisfied with the intervention, especially with the consultations with the physiotherapist. Conclusions Although the expected extent of effects could not be determined for the IG, stabilisation effects could be demonstrated. These stabilisation effects shown for the IG might be attributed to the intervention. The effects might have been greater without the COVID-19 pandemic. Trial registration. German Register of Clinical Trials, drks.de. Identifier: DRKS00014952. Registered 20/06/2018. Date and version identifier 25/04/2019; version 1.

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Trends in der Prävalenz von Demenz und Parkinson – Eine Analyse auf Basis aller gesetzlich versicherten Personen im Alter 65+in Deutschland zwischen 2009 und 2012

Cited by 14 publications

References 47 publications

Attitudes of legal guardians and legally supervised persons with and without previous research experience towards participation in research projects: A quantitative cross-sectional study

Attitudes of legal guardians and legally supervised persons with and without previous research experience towards participation in research projects: A quantitative cross-sectional study

Zeitliche Veränderung der Prävalenz von Parkinson-Diagnosen in Deutschen Hausarzt- und Neurologischen Praxen von 2010 bis 2019

Evaluation of an individualized, tablet-based physiotherapy training programme for patients with Parkinson’s disease: the ParkProTrain study, a quasi-randomised controlled trial

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