Trends in ectopic pregnancy, hydatidiform mole and miscarriage in the largest obstetrics and gynaecology hospital in China from 2003 to 2013

Abstract

BackgroundEctopic pregnancies, miscarriages and hydatidiform moles are the major types of pathological pregnancies in the early gestations of pregnancy and constitute an important public health problem. The trends and incidences of these pathological pregnancies may vary by ethnicity and geographical regions. This has not been fully investigated in the Chinese population. In this study we retrospectively report the trends of pathological pregnancies in Chinese population.MethodsData on 22,511 women with ectopic pregnancy, hydatidiform mole and miscarriage were collected from the largest obstetrics and gynaecology hospital in China from 2003 to 2013. Data included age at diagnosis and the annual number of women with diagnosed ectopic pregnancy, hydatidiform mole and miscarriage.ResultsThe total number of ectopic pregnancy, hydatidiform mole and miscarriage was increased 3.5folds in 2013 compared to 2003. Ectopic pregnancy is the leading pathological pregnancy and miscarriage is increasing at a greater rate among the pathological pregnancies. The median age of women with hydatidiform mole at diagnosis significantly increased from 25.5 years to 29 years (p = 0.002), however the median age for other pathological pregnancies was not different between 2003 and 2013. The number of women with hydatidiform mole at diagnosis who were over 40 years old has increased. The mean maternal age is increased from 28.1 years old in 2003 to 29.4 years old in 2013 in this hospital.ConclusionWe speculate that the increased maternal age may contribute to the increase in these pathological pregnancies between 2003 and 2013 in China.

The Reasons and Strategies of High Cesarean Section Rate from Chinese Obstetricians and Midwives Perspective in the Public Hospitals: An Interpretative Phenomenologic Analysis

“…and strategy from obstetricians and midwives' perspective, differing from some other studies that usually make a quantitative test of reasons to CS and qualitative studies emphasized on women's perception. Women registered in a primary hospital usually referred to secondary and tertiary hospitals since obstetric complications happened increasingly in recent years [9]. In this case, the study aims to describe obstetricians and midwives' perceptions of the essence of the increasing CSR at the tertiary and secondary levels of hospitals in China.…”

Association between gestational trophoblastic disease (GTD) history and clinical outcomes in in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) cycles

“…The disadvantage of this retrospective study is that the sample size was small, which may be related to the decreasing incidence of GTD in recent years [ 33 ] and the low secondary infertility rate after GTD [ 34 – 36 ]. There are still some patients who have not received embryo transfer, and further follow-up of these patients is needed.…”

Ectopic pregnancy in China during 2011–2020: a single-centre retrospective study of 9499 cases

“…China is a developing country with an incidence of EP estimated at 2.5% in 2004 [ 5 ]. The number of EP cases admitted to Fudan University Obstetrics and Gynaecology Hospital, a large tertiary hospital in Shanghai, China, increased from 698 in 2003 to 1860 in 2013 [ 6 ]. After the implementation of the one-child policy in China in 1979, the total fertility rate (defined as the average number of children born per woman) was reduced from 2.9 to around 1.6 [ 7 ].…”

“…After the implementation of the one-child policy in China in 1979, the total fertility rate (defined as the average number of children born per woman) was reduced from 2.9 to around 1.6 [ 7 ]. This gave rise to a delay in childbearing, as reflected by the increasing average age of puerpera from 28.1 years old in 2003 to 29.4 in 2013 in Fudan University Obstetrics and Gynaecology Hospital [ 6 ], and an increase in caesarean section rate [ 8 ].…”