Trends in Frailty Prevalence Among Older Adults in Korea: A Nationwide Study From 2008 to 2020

Kang, Min-gu; Kim, Oh Seok; Hoogendijk, Emiel O.

doi:10.3346/jkms.2023.38.e157

Cited by 9 publications

(1 citation statement)

References 41 publications

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“…The elderly population in Korea is steadily increasing, expected to transition into a super-aged society by 2025 1) . In 2020, the frailty prevalence among the elderly was 23%, reaching 56% when considering pre-frailty, indicating that over half of the aged 65 and older population is at risk of frailty 2) . Recognizing the importance of preventing frailty for healthy aging and overall well-being in older adults, it becomes imperative to discuss appropriate interventions and timely strategies.…”

Section: Introductionmentioning

confidence: 99%

Determining the Onset Age for Early Intervention of Oral Frailty

Hong,

Kim

2024

J Dent Hyg Sci

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Background: Oral frailty is defined as the functional decline of the oral function due to aging, and it is associated with frailty and chronic disease. Most of the frailty intervention is for adults aged 65 years and older. However, early intervention for preventive disorder is most important. The objective of this study was to identify the age at which oral frailty surpass the "normal" range. Methods: This cross-sectional study included 719 adults (aged 30∼89 years) residing in Gangwon province in May 2023. Risk of oral frailty was assessed using criteria from The Korean Academy of Geriatric Dentistry including oral function such as swallowing and mastication, and frailty. Frailty was assessed using the Kihon Checklist. To determine when oral frailty surpass the "normal" status, statistical analysis including chi-squared tests and multiple logistic regression analysis were performed using R (ver. 4.3.1). Results: There were 388 (54.0%) individuals who had a "normal" status risk of oral frailty. The risk of oral frailty was higher in the 50∼54 age group compared to the 30∼34 age group (odds ratio [OR] 0.50, 95% confidence interval [CI] 0.28∼0.91), after adjusting for gender, education, income, occupation, and frailty (OR 0.46, 95% CI 0.22∼0.94). This means that from 50∼54 years old, regardless of gender, education, income, occupation, or frailty condition, there is a distinction from the "normal" status. Conclusion: We found that intervention for oral frailty is needed starting from age 50 years. This is the stage where early indications of oral frailty become apparent. Early intervention for oral frailty can lead to a decrease in the prevalence of diseases and medical expenditure. Therefore, early intervention in middle-aged adults of oral frailty is necessary to improve the quality of life related to oral health.

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Section: Introductionmentioning

confidence: 99%

Determining the Onset Age for Early Intervention of Oral Frailty

Hong,

Kim

2024

J Dent Hyg Sci

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Higher serum uric acid as a risk factor for frailty in older adults: A nationwide population‐based study

Kang,

Baek,

et al. 2024

J cachexia sarcopenia muscle

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BackgroundUric acid (UA), the terminal breakdown product of purine metabolism, possesses contradictory roles, functioning both as an inflammatory mediator and as an antioxidant. Its clinical relevance, particularly in geriatric populations, remains a topic of ongoing debate. Aiming to elucidate whether circulating UA is detrimental or beneficial to human health, we investigate the association between serum UA concentrations and the frailty index—a comprehensive measure of biological aging in a nationally representative cohort of community‐dwelling older adults.MethodsWe conducted a population‐based, cross‐sectional study utilizing data from the Korea National Health and Nutrition Examination Survey. The sample included 4268 participants aged 65 years and above. A deficit accumulation frailty index (FI) was constructed using 38 items that assess physical, cognitive, psychological, and social domains. Based on the FI, participants were categorized into non‐frail (FI ≤ 0.15), pre‐frail (0.15 < FI ≤ 0.25), or frail (FI > 0.25). Serum UA levels were quantified through a colorimetric enzymatic assay.ResultsAfter controlling for confounders such as age, sex, socioeconomic status (including income and education level), lifestyle factors (smoking status), and medical history (hypertension, diabetes, dyslipidemia, stroke, cardiovascular diseases), and body mass index, serum UA levels were observed to be significantly higher in frail participants compared with their non‐frail counterparts (P < 0.001). Furthermore, serum UA concentrations demonstrated a positive correlation with the FI (P < 0.001), and the odds ratio for frailty per 1 mg/dL increase in serum UA was 1.22 (P < 0.001). Additionally, older adults in the highest quartile of UA levels exhibited a significantly higher FI and 1.66‐fold increased odds of frailty compared with those in the lowest quartile (P = 0.011 and P = 0.005, respectively).ConclusionsThese findings suggest that elevated circulating UA levels may act as a pro‐aging factor rather than an anti‐aging one in older adults, highlighting its potential role in accelerating biological aging. The data further support the utility of serum UA as a potential blood‐based biomarker for frailty in this demographic, contributing to the expanding evidence on its significance in geriatric health assessments.

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Prevalence of frailty in senile osteoporosis: A systematic review and meta-analysis

Hu,

Xu,

et al. 2025

Archives of Gerontology and Geriatrics

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Trends in Frailty Prevalence Among Older Adults in Korea: A Nationwide Study From 2008 to 2020

Cited by 9 publications

References 41 publications

Determining the Onset Age for Early Intervention of Oral Frailty

Determining the Onset Age for Early Intervention of Oral Frailty

Higher serum uric acid as a risk factor for frailty in older adults: A nationwide population‐based study

Prevalence of frailty in senile osteoporosis: A systematic review and meta-analysis

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