Trends in hospitalizations for community-acquired pneumonia in Spain: 2004 to 2013

Miguel-Díez, Javier de; Jiménez‐García, Rodrigo; Hernández-Barrera, Valentín; Jiménez‐Trujillo, Isabel; Miguel‐Yanes, José M. de; Méndez‐Bailón, Manuel; López‐de‐Andrés, Ana

doi:10.1016/j.ejim.2016.12.010

Cited by 44 publications

(46 citation statements)

References 40 publications

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“…Other studies showed that the incidence of CAP in Spanish adults requiring hospitalization rose from 1.42 cases per 1000 persons/year in 2004 to 1.63 cases in 2013. The incidence increased in both sexes (from 2.08 to 2.27 in males and from 0.92 to 1.16 in females) and in the older age groups (from 10.06 to 11.00 in the 75-84 year group, and from 2.11 to 25.84 in the ≥85 year group) [7]. Interestingly, two recent studies showed an increase in the incidence of CAP in COPD patients (from 13.44 per 1000 persons/year in 2004-2005 to 16.40 cases in 2012-2013) and in patients with diabetes (from 8.14 per 1000 persons/year in 2004 to 9.23 cases in 2013); COPD and diabetes are both important and frequent comorbidities in CAP patients [7][8][9].…”

Section: Introductionmentioning

confidence: 96%

Defining Community-Acquired Pneumonia as a Public Health Threat: Arguments in Favor from Spanish Investigators

et al. 2020

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Despite advances in its prevention, pneumonia remains associated with high morbidity, mortality, and health costs worldwide. Studies carried out in the last decade have indicated that more patients with community-acquired pneumonia (CAP) now require hospitalization. In addition, pneumonia management poses many challenges, especially due to the increase in the number of elderly patients with multiple comorbidities, antibiotic-resistant pathogens, and the difficulty of rapid diagnosis. In this new call to action, we present a wide-ranging review of the information currently available on CAP and offer some reflections on ways to raise awareness of this disease among the general public. We discuss the burden of CAP and the importance of attaining better, faster microbiological diagnosis and initiating appropriate treatment. We also suggest that closer cooperation between health professionals and the population at large could improve the management of this largely preventable infectious disease that takes many lives each year.

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Section: Introductionmentioning

confidence: 96%

Defining Community-Acquired Pneumonia as a Public Health Threat: Arguments in Favor from Spanish Investigators

et al. 2020

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“…Admissions for pneumonia generate considerable health care expenditure. The mean hospital stay of patients affected by pneumonia is around 7 days [4], and the direct cost of each admission is more than €1500 in Spain [5].…”

Section: Introductionmentioning

confidence: 99%

Influence of Pneumonia on the Survival of Patients with COPD

Vázquez

Cano

et al. 2020

JCM

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Background: Pneumonia is a frequent infection. Chronic obstructive pulmonary disease (COPD) can present with comorbidities, including pneumonia. It is known that COPD worsens the evolution of pneumonia, but few studies describe the impact of pneumonia on COPD evolution. This study analyzes the influence of pneumonia on the survival of COPD patients. Methods: Observational study of a cohort of 273 patients with COPD who attended spirometry in 2011, with a prospective follow-up of six years. Patients were divided into two groups according to their acquisition of pneumonia during follow-up. The difference in survival between the two groups was analyzed. Results: Survival was lower in the group with pneumonia compared with that without pneumonia (p = 0.000), both globally and after stratification by COPD phenotype. Pneumonia (Hazard Ratio -HR- 2.65; 95% Confidence Interval -CI- 1.57–4.48), advanced age (HR 1.08; 95% CI 1.03–1.09), and high Charlson index (HR 1.31; 95% CI 1.17–1.47) were identified as risk factors independently associated with mortality, while a high body mass index (HR 0.92; 95% CI 0.87–0.96) was identified as a protective factor. Conclusions: Pneumonia is associated with worse prognosis in COPD patients. It is important to take into account this comorbidity for a comprehensive care of these patients.

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“…[1] Pneumonia is in the differential diagnosis of respiratory tract symptoms that are the most common cause of urgent emergency department visits, with high hospitalization and mortality rates worldwide. [2][3][4][5][6][7] The diagnosis of pneumonia usually depends on symptoms and chest imaging. [7,8] However, it is not feasible to obtain chest radiography in all patients admitted to the hospital who present with acute fever or respiratory symptoms.…”

Section: Introductionmentioning

confidence: 99%

Clinical characteristics and predictors of pneumonia in patients presenting fever or respiratory symptoms with normal or low leukocyte counts: a retrospective study

Wang¹,

Liu²,

Li³

et al. 2020

Preprint

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Background Many patients went to the hospital presenting with acute fever, or respiratory symptoms, most of whom have a normal or low leukocyte counts. The aim of this study was to investigate the clinical characteristics and predictors of pneumonia in those patients. Methods In this retrospective study, adult patients (≥ 18 years old) presenting with acute fever or respiratory symptoms with normal or low leukocyte counts (≤ 9.5 × 109/L) in Peking Union Medical College Hospital between 26 January 2020 and 10 March 2020 were included. Patients were categorized into groups with pneumonia or upper respiratory tract infection (URTI) according to chest CT scans. Logistic regression was used to explore predictors of pneumonia. Results A total of 195 patients were included, 63 of whom were diagnosed with pneumonia. The median maximum body temperature was 38.5 °C (38.0-38.8 °C) in patients with pneumonia and 37.5 °C (37.4–37.8 °C) in the other group. There was a significant difference in high-sensitivity C-reactive protein (hsCRP) levels between the two groups (0.21 (0-3.74) versus 33.4 (15.5–75.5) mg/L, p < 0.001). Multivariable regression showed that the predictive values of pneumonia were older age (OR 1.06, 95% CI 1.02–1.10, p = 0.004), cough (OR 0.18, 95%CI 0.06–0.56; p = 0.003), higher temperature (OR 3.36, 95%CI 1.16–9.71; p = 0.025) and higher hsCRP level (OR 1.05, 95%CI 1.02–1.09; p = 0.003). The optimal cutoff values based on the ROC curve analysis were a temperature of 37.8 °C and a hsCRP level of 1.64 mg/L. Conclusions Patients with older age, cough, higher temperature and higher hsCRP level were more inclined to have pneumonia. Temperatures higher than 37.8 °C were a potential predictor of pneumonia in patients with normal or low leukocyte counts in the early stage. However, a hsCRP level less than 1.64 mg/L could rule out most cases of pneumonia.

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Trends in hospitalizations for community-acquired pneumonia in Spain: 2004 to 2013

Cited by 44 publications

References 40 publications

Defining Community-Acquired Pneumonia as a Public Health Threat: Arguments in Favor from Spanish Investigators

Defining Community-Acquired Pneumonia as a Public Health Threat: Arguments in Favor from Spanish Investigators

Influence of Pneumonia on the Survival of Patients with COPD

Clinical characteristics and predictors of pneumonia in patients presenting fever or respiratory symptoms with normal or low leukocyte counts: a retrospective study

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