Trends in Incidence of Brain and Central Nervous System Tumors in Norway, 1970–1999

Abstract

The aim of this study was to investigate trends in the incidence of childhood and adult brain and central nervous system (CNS) tumors in Norway from 1970 through 1999. In this period, a total of 14,641 patients were diagnosed with a primary benign or malignant neoplasm of the brain and CNS. Age-adjusted incidence rates were reported together with results of loglinear regression and an age-period-cohort model based on the Poisson regression model. In children (<15 years), the proportion of brain and CNS tumors was 28.2% (1,042/3,697) of all new cancer cases compared with 2.8% in adults (13,599/492,237). The overall rate of brain and CNS tumors increased during the study period from 6.49 to 12.02 cases per 100,000 person-years. A trend of leveling off in incidence of most tumor categories during the study period was indicated with a possible continuing increase in the period 1995–1999, especially in the age group 0–4 years and in patients aged 60 years or more. Age and period together provided a satisfactory model in patients being <60 years of age and less completeness of diagnosis was found in males compared with females, possibly due to the distribution in males of more aggressive tumors.

Increasing incidence and continued dismal outcome of primary central nervous system lymphoma in Norway 1989–2003

“…1 In Norway, the rates of central nervous system tumors almost doubled from 1970 to 1999. 33 However, between 1989 and 2003, the increase in primary brain tumors (excluding tumors in meninges, corpus pineale, hypophysis, and cranial nerves) was moderate. 34 The average annual incidence rate was 85.7 per million (95% CI, 83.4-87.9 per million), and the EAPC was 2.3% (95% CI, 1.7-2.9%; P < .001) (Fig.…”

Descriptive epidemiology of malignant and nonmalignant primary spinal cord, spinal meninges, and cauda equina tumors, United States, 2004‐2007

“…6 However, our results differ from a study in Norway that found equal proportions of spinal cord and spinal meninges, and a study in Croatia finding that > 1 = 2 of the tumors diagnosed in this population were located in the spinal meninges. 17,18 Possible explanations for these differences may be attributed to small sample size or population differences within the Norway and Croatia data sets. Results from our analyses confirm previous findings of frequencies of histology types and sex differences.…”

Primary spinal cord tumors: review of 678 surgically treated patients in Japan. A multicenter study

“…Primary spinal cord tumors are one of the rarest categories of tumors, representing about 4-16 % of all tumors arising from the central nervous systems (CNS) according to previous reports [1][2][3][4][5][6][7][8][9][10][11][12][13]. Because of variation in population sizes studied and classification of tumors, the frequencies of different spinal cord tumors vary among these reports.…”