2018
DOI: 10.1016/j.ijporl.2018.04.008
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Trends in management of obstructive sleep apnea in pediatric patients with Down syndrome

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Cited by 37 publications
(28 citation statements)
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“…After 4 months, 22 regularly used (defined as >4 hours per night for >50% of the night) prescribed respiratory support. These findings supported the high prevalence of OSA in Down syndrome as seen in previous studies . In addition, they found that 56% of the patients were adherent to their respiratory support, which differs from previous literature .…”
Section: Introductionsupporting
confidence: 88%
“…After 4 months, 22 regularly used (defined as >4 hours per night for >50% of the night) prescribed respiratory support. These findings supported the high prevalence of OSA in Down syndrome as seen in previous studies . In addition, they found that 56% of the patients were adherent to their respiratory support, which differs from previous literature .…”
Section: Introductionsupporting
confidence: 88%
“…Adenotonsillectomy is the first‐line treatment for children with OSA and has been shown to provide therapeutic benefit to children with DS and OSA who have tonsillar hypertrophy . However, it is estimated that only 16% to 33% of children with DS have resolution of their OSA (defined as an apnea‐hypopnea index [AHI] <1 event/hr) following adenotonsillectomy . In the case of OSA refractory to adenotonsillectomy, sites of residual obstruction include base of tongue obstruction, pharyngeal collapse, and crowding associated with obesity and lingual tonsil hypertrophy.…”
Section: Introductionmentioning
confidence: 99%
“…3 However, it is estimated that only 16% to 33% of children with DS have resolution of their OSA (defined as an apnea-hypopnea index [AHI] <1 event/hr) following adenotonsillectomy. 8 In the case of OSA refractory to adenotonsillectomy, sites of residual obstruction include base of tongue obstruction, pharyngeal collapse, and crowding associated with obesity and lingual tonsil hypertrophy. Approximately 63% of patients with DS who have persistent OSA following adenotonsillectomy have glossoptosis.…”
Section: Introductionmentioning
confidence: 99%
“…A high prevalence of OSAS (up to 78%) has been reported in children with Trisomy 21 and frequently oAHI exceeds 5 episodes/h, a finding consistent with moderate‐to‐severe disease . Several abnormal clinical features predispose patients with Trisomy 21 to OSAS and hypoventilation, namely midfacial and mandibular hypoplasia, shortened palate, relative macroglossia, laryngomalacia, narrow nasopharynx, pharyngeal hypotonia, and adenotonsillar hypertrophy .…”
Section: Trisomy 21 Osas and Response To Adenotonsillectomymentioning
confidence: 89%
“…Interventions offered to children with Down syndrome for the treatment of OSAS are mostly based on clinical experience and not on high‐quality evidence. For example, more studies are required to clarify: the efficacy of weight loss; the compliance with and the efficacy of oral appliances, continuous positive airway pressure (CPAP) and bilevel positive airway pressure (BPAP); and the role of additional surgical procedures like revision adenoidectomy, supraglottoplasty, lingual tonsillectomy, posterior midline glossectomy, uvulopalatopharyngoplasty, and craniofacial surgery …”
Section: Trisomy 21 Osas and Response To Adenotonsillectomymentioning
confidence: 99%