Background
Disparities in late-stage breast or colorectal cancer diagnosis in younger populations are associated with social determinants of health (SDOH; education, poverty, housing, employment). We hypothesized that, in older Medicare beneficiaries, disparities in late-stage cancer diagnosis between Hispanic, non-Hispanic Black (NHB), and non-Hispanic White (NHW) patients would be associated with SDOH, comorbidities, and primary care physician (PCP) access.
Methods
We analyzed 2005–2017 Texas Cancer Registry data linked with Medicare data for patients aged ≥ 66 (
n
= 86,501). Variables included age at diagnosis, sex, comorbidities, poverty level, education, PCP, and relevant cancer screening within 1 year.
Results
For breast cancer in women
(Hispanic,
n
= 6380; NHW,
n
= 39,225; NHB,
n
= 4055), a fully adjusted model showed significantly higher odds of late-stage cancer diagnosis only in NHB patients (odds ratio [OR] 1.11, 95% confidence interval [CI] 1.01–1.22) compared with NHW; adjustment for comorbidities and SDOH partially decreased the odds of late-stage diagnosis relative to NHWs. Interaction terms between race-ethnicity and poverty were not significant.
For colorectal cancer
, a fully adjusted multivariate model showed significantly higher odds of late-stage diagnosis only among NHBs (
n
= 3318, OR 1.29, 95% CI 1.19–1.40) relative to NHWs (
n
= 27,470); adjustment for SDOH partially decreased the odds of late-stage diagnosis in NHB patients. Interaction terms between race-ethnicity and poverty were not significant.
Conclusion
Racial disparities in late-stage breast and colorectal cancer diagnoses remain after adjustment for SDOH and clinically relevant factors, underscoring the need to optimize access to screening and timely cancer treatment in racial/ethnic minorities.
Supplementary Information
The online version contains supplementary material available at 10.1007/s40615-022-01491-4.