Trends in prevalence and risk factors of childhood asthma in Fuzhou, a city in Southeastern China

Tang, Suping; Liu, Yanlin; Wang, Shibiao; Weng, Shengfeng; Shen, Chen; Zhang, Min-Jun; Li, Dong; Guo, Yihua; Dongru, Lin; Hua, Yun-han; Wang, Deyun

doi:10.3109/02770903.2014.952434

Cited by 13 publications

(13 citation statements)

References 14 publications

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“…Using a split AC system was a risk factor, possibly because cleaning these devices is difficult, which may lead to the accumulation of allergens and other substances. 26 In China, air conditioning systems are also significantly associated with asthma in schoolchildren, 27 although these systems may protect against traffic-related exposures at home, as reported in Singaporean children. 28 Finally, a high frequency of paracetamol intake was a risk factor for asthma in our study, which is in agreement with global ISAAC findings.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of asthma and allergies in 13–14-year-old adolescents from Luanda, Angola

Arrais¹,

Lulua²,

Quifica³

et al. 2017

int j tuberc lung dis

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Section: Discussionmentioning

confidence: 99%

Prevalence of asthma and allergies in 13–14-year-old adolescents from Luanda, Angola

Arrais¹,

Lulua²,

Quifica³

et al. 2017

int j tuberc lung dis

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“…Poor ventilation in indoor bedrooms is common, especially in deprived areas [ 28 ]. In some regions and because of the high temperature, windows and doors are open most of the time, and some studies revealed that in those settings natural ventilation is a protective factor for asthma [ 29 ]. The climate also predisposes to insect bites that induce papular urticaria.…”

Section: Introductionmentioning

confidence: 99%

Particularities of allergy in the Tropics

Caraballo

Zakzuk

Lee

et al. 2016

World Allergy Organization Journal

128

145

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Allergic diseases are distributed worldwide and their risk factors and triggers vary according to geographical and socioeconomic conditions. Allergies are frequent in the Tropics but aspects of their prevalence, natural history, risk factors, sensitizers and triggers are not well defined and some are expected to be different from those in temperate zone countries. The aim of this review is to investigate if allergic diseases in the Tropics have particularities that deserve special attention for research and clinical practice. Such information will help to form a better understanding of the pathogenesis, diagnosis and management of allergic diseases in the Tropics. As expected, we found particularities in the Tropics that merit further study because they strongly affect the natural history of common allergic diseases; most of them related to climate conditions that favor permanent exposure to mite allergens, helminth infections and stinging insects. In addition, we detected several unmet needs in important areas which should be investigated and solved by collaborative efforts led by the emergent research groups on allergy from tropical countries.Electronic supplementary materialThe online version of this article (doi:10.1186/s40413-016-0110-7) contains supplementary material, which is available to authorized users.

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“…The onset of asthma onset occurs before the age of 12 (years) in over half the cases. The past 20 years have seen a significant increase in the prevalence of asthma in children (Tang et al, 2015). The pathogenesis of asthma is related to multiple risk factors including environmental factors such as vehicular pollution, and genetic factors such as polymorphisms in the interleukin (IL)-4 and ORMDL3 genes (Favarato et al, 2014;Tang et al, 2014;Zhai et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

Meta-analysis of the IL-10 promoter polymorphisms and pediatric asthma susceptibility

Zy¹,

Bj²,

Wan³

et al. 2016

Genet. Mol. Res.

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ABSTRACT. The results of previous epidemiological studies exploring the relationship between interleukin-10 (IL-10) promoter polymorphisms and susceptibility to pediatric asthma are not consistent. Therefore, we have performed a systematic review and meta-analysis to provide a more convincing conclusion. Odds ratios (OR) with their 95% confidence intervals (CIs) were used to evaluate the strength of association between the IL-10 promoter polymorphisms and susceptibility to pediatric asthma. Publication bias was examined by Begg's funnel plots and the Egger test. A detailed literature search based on stringent parameters yielded sixteen relevant studies, comprising 2494 cases and 2160 controls. The overall population showed no significant association between the IL-10 -1082G/A polymorphism and pediatric asthma risk in any of the genetic models and atopic status subgroups. However, there was no evidence of a significant association between the other two polymorphisms (-819C/ T and -592C/A) and pediatric asthma in our study. No significant publication bias was observed in this meta-analysis. The results of this study indicate that the IL-10 -1082G/A polymorphism might be a risk factor for asthma in children. However, because of the small sample size included in the subgroup analyses, the results should be interpreted with caution.

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Trends in prevalence and risk factors of childhood asthma in Fuzhou, a city in Southeastern China

Abstract: The prevalence of asthma in childhood has increased significantly during the past 20 years in Fuzhou.

Cited by 13 publications

References 14 publications

Prevalence of asthma and allergies in 13–14-year-old adolescents from Luanda, Angola

Prevalence of asthma and allergies in 13–14-year-old adolescents from Luanda, Angola

Particularities of allergy in the Tropics

Meta-analysis of the IL-10 promoter polymorphisms and pediatric asthma susceptibility

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