Trends in the Diels–Alder reaction in polymer chemistry

Abstract

The Diels–Alder (DA) reaction is regarded as quite a useful strategy in organic and macromolecular syntheses.

Diels–Alder Cycloadditions of Bio-Derived Furans with Maleimides as a Sustainable «Click» Approach towards Molecular, Macromolecular and Hybrid Systems

“…The broad investigations describing the synthesis of various dynamic polymeric materials and composites using DA reactions (such as structural materials, supramolecular systems, hydrogels, coatings with tunable adhesion), which have promising potential for biomedical applications or smart materials development, were highlighted in some recent reviews [80][81][82][83]. Dynamers with many different structural types can be synthesized using the fmDA approach depending on the structure and ratio of the initial components.…”

“…Dynamers with many different structural types can be synthesized using the fmDA approach depending on the structure and ratio of the initial components. The application of furan-and maleimide-functionalized bifunctional monomers or end-capped linear pre-polymers provides the formation of linear dynamic polymers and co-polymers, while the incorporation of three or more furanic or maleimide functionalities into the structure of monomers leads to the formation of branched, hyperbranched or cross-linked architectures [20,81]. Several types of dendritic compound were also prepared using the fmDA approach [20,84].…”

New Insights into the (A)Synchronicity of Diels–Alder Reactions: A Theoretical Study Based on the Reaction Force Analysis and Atomic Resolution of Energy Derivatives

“…Some of the most striking examples include the synthesis of the steroids cortisone and cholesterol by Woodward et al [ 7 ] and the preparation of disodium prephenate, a biosynthetic precursor of the amino acids phenylalanine and tyrosine [ 8 ]. In addition to its relevance in natural products chemistry, the DA reaction and its variants are also utilized for many other purposes, such as in the design of polymers and drug delivery systems [ 9 , 10 , 11 ], as well as in the synthesis of agrochemicals [ 12 , 13 ].…”

New Insights into the (A)Synchronicity of Diels-Alder Reactions: A Theoretical Study Based on the Reaction Force Analysis and Atomic Resolution of Energy Derivatives

“…Some of the most striking examples include the synthesis of the steroids cortisone and cholesterol by Woodward et al [7] and the preparation of disodium prephenate, a biosynthetic precursor of the amino acids phenylalanine and tyrosine [8]. In addition to its relevance in natural products chemistry, the DA reaction and its variants are also utilized for many other purposes, such as in the design of polymers and drug delivery systems [9][10] [11], as well as in the synthesis of agrochemicals [12] [13].…”