Trends in the national outcomes and costs for claudication and limb threatening ischemia: Angioplasty vs bypass graft

Abstract

PTA has altered the treatment paradigm for lower limb ischemia with an increase in costs and procedures. It is unclear if this represents an increase in patients or number of treatments per patient. Although mortality is slightly lower with PTA for all indications, amputation rates for limb-threat patients appear higher, as does the average cost. Longitudinal studies are necessary to determine the appropriateness of PTA in both claudication and limb-threat patients. The mortality benefit with PTA may be ultimately lost, and average costs elevated, if multiple interventions are performed on the same patients.

Assessing the Perioperative Safety of Common Femoral Endarterectomy in the Endovascular Era

“…10,15,30 A high-technical failure rate of up to 10%, combined with worse durability than CFE could potentially lead to multiple interventions, even culminating in CFE, that may increase risk of periprocedural complications and escalate costs. 6,16 The CFE can still be considered as a safe and durable firstline treatment for CFA occlusive disease. The long-term safety of ET in the CFA has not been evaluated, and long-term morbidity secondary to injury or obstruction of the profunda femoris and complications from flexion across a joint remain unclear.…”

Reporting standards of the Society for Vascular Surgery for endovascular treatment of chronic lower extremity peripheral artery disease

“…As a result, the actual cost per patient may be higher than that reported in the current literature and should use a method to account for multiple procedures on the same patient. [83][84][85] Finally, analyses of cost and utilization are generally limited by differences in coding because data may be incomplete or biased by those annotating the data. With the continued revision and adoption of such systems as the 10 th Revision of the International Statistical Classification of Disease and Related Health Problems, reporting standardization will help to overcome such limitations.…”

Selective inhibition of plasma membrane calcium ATPase 4 improves angiogenesis and vascular reperfusion

“…In some patients, bypass surgery and interventional endovascular procedures can successfully restore blood flow to the ischaemic tissue [1,33]. However, the distribution and diffuseness of arterial occlusions preclude surgical revascularization in a high proportion of patients [1].…”