Trends in the prevalence of asthma and allergic rhinitis in Italy between 1991 and 2010

Marco, Roberto de; Cappa, Veronica; Accordini, Simone; Rava, Marta; Antonicelli, Leonardo; Bortolami, Oscar; Braggion, Marco; Bugiani, Massimiliano; Casali, Lucio; Cazzoletti, Lucia; Cerveri, Isa; Fois, Alessandro Giuseppe; Girardi, Paolo; Locatelli, Francesca; Marcon, Alessandro; Marinoni, Alessandra; Panico, Maria Grazia; Pirina, Pietro; Villani, Simona; Zanolin, Maria Elisabetta; Verlato, Giuseppe

doi:10.1183/09031936.00061611

Cited by 189 publications

(185 citation statements)

References 46 publications

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“…During the past 20 years, overall asthma prevalence has increased by 38%, in parallel with a similar increase in asthmalike symptoms and allergic rhinitis [43]. Although prevalence rates have been studied more extensively in children, most studies confirm a real increase in asthma prevalence among adults as well.…”

Section: Epidemiology Of Adult-onset Asthmamentioning

confidence: 71%

Adult-onset asthma: is it really different?

Nijs¹,

Venekamp²,

Bel³

2013

Eur Respir Rev

251

205

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Asthma that starts in adulthood differs from childhood-onset asthma in that it is often non-atopic, more severe and associated with a faster decline in lung function.Understanding of the underlying mechanism of adult-onset asthma and identification of specific phenotypes may further our understanding of pathophysiology and treatment response, leading to better targeting of both existing and new approaches for personalised management. Pivotal studies in past years have led to sustained progress in many areas, ranging from risk factors for development, identification of different phenotypes, and introduction of new therapies.This review highlights and discusses literature on adult-onset asthma, with special focus on the differences from childhood-onset asthma, risk factors for development, phenotypes of adultonset asthma and new approaches for personalised management.

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Section: Epidemiology Of Adult-onset Asthmamentioning

confidence: 71%

Adult-onset asthma: is it really different?

Nijs¹,

Venekamp²,

Bel³

2013

Eur Respir Rev

251

205

View full text Add to dashboard Cite

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“…An important finding of our study is the high prevalence of respiratory allergic disease, rhinitis and asthma due to pollen, mites and pet dander (see Table 2). Particularly the prevalence of asthma appears quite higher in patients who report food anaphylaxis than in the general population of Torino, the most populous town of the same Region, according to a recent epidemiological study [27]. A history of asthma appears to be a major risk factor for life-threatening anaphylactic reactions to food [28][29][30], but it is not particularly specific, as about a third of food allergic patients have asthma.…”

Section: Resultsmentioning

confidence: 99%

Incidence of food anaphylaxis in Piemonte region (Italy): data from registry of Center for Severe Allergic Reactions

et al. 2013

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There are wide differences in estimated incidence and prevalence of anaphylaxis because of the absence, until recently, of a universal consensus on the definition of anaphylaxis and the different source of collected data. We aimed to estimate the incidence of food anaphylaxis based on the database of Piemonte Region (Italy) Reference Center for Severe Allergic Reactions. All cases of severe food allergic reactions reported in 2010 were studied. Clinical data associated to the reports were evaluated according to National Institute of Allergy and Infectious Disease and Food Allergy and Anaphylaxis Network diagnostic criteria of anaphylaxis. 75 % of the 778 cases were classified as food anaphylaxis (incidence of 13/100,000 personyears, ranging from 9.9 in adults to 29/100,000 person-years in children). Nuts were the most frequent foods causing anaphylaxis. Milk and eggs were responsible for anaphylaxis more often in children, while peach, vegetables and crustaceans were in adults. Cardiovascular symptoms were more frequent in adults. Gastrointestinal involvement was more frequent in children. A high prevalence of respiratory allergic comorbidities was observed. Food is an important cause of anaphylaxis, particularly in subjects with respiratory allergic comorbidities. Children and adults differ in triggers and clinical presentation of anaphylaxis.Keywords: Anaphylaxis, Food allergy, Epidemiology, Allergy Introduction Population-based studies estimate the incidence of anaphylaxis in western countries to be in the range of 4-50 per 100,000 person-years [1, 2], with a true lifetime prevalence in the range of 0.05-2 % [3]. Foods are reported to be the most important trigger of anaphylaxis, being responsible for 33.2-56 % of all anaphylaxis cases [4]. The other two principal triggers of anaphylaxis are insect stings and drugs [1,5]. The relative contribution of each of these triggers to anaphylaxis may differ according to the study design, study population, or geographic area. The wide differences in the estimated incidences and prevalences of anaphylaxis are the direct result of the absence, until recently, of a universal consensus on the definition of anaphylaxis and the different source of collected data. For this reason in 2005 the National Institute of Allergy and Infectious Disease (NIAID) and the Food Allergy and Anaphylaxis Network (FAAN) developed a very useful preliminary definition, based on diagnostic criteria [6]. The symposium defined anaphylaxis as: "a serious allergic reaction that is rapid in onset and may cause death". Clinically, involvement of at least two organs (skin or mucosal tissue, cardiovascular apparatus, breathing apparatus, gastrointestinal tract) is required, or a sudden reduced blood pressure along with a temporal relationship (generally minutes) to a potential causative agent. A problematic issue with this definition, which may explain the under-reporting or misreporting of anaphylaxis cases, is the failure to agree among health care providers on the severity threshold for classi...

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“…Allergic diseases have become one of the most important health issues worldwide (Bocking et al 2012;de Marco et al 2012;D'Amato et al 2013). Sensitisation and allergic diseases increase with socioeconomic status and living in large cities (Langen et al 2013).…”

Section: Introductionmentioning

confidence: 99%

Plants remember past weather: a study for atmospheric pollen concentrations of Ambrosia, Poaceae and Populus

Matyasovszky

Makra

Csépe

et al. 2014

Theor Appl Climatol

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After extreme dry (wet) summers or years, pollen production of different taxa may decrease (increase) substantially. Accordingly, studying effects of current and past meteorological conditions on current pollen concentrations for different taxa have of major importance. The purpose of this study is separating the weight of current and past weather conditions influencing current pollen productions of three taxa. Two procedures, namely multiple correlations and factor analysis with special transformation are used. The 11-year (1997The 11-year ( -2007) data sets include daily pollen counts of Ambrosia (ragweed), Poaceae (grasses) and Populus (poplar), as well as daily values of four climate variables (temperature, relative humidity, global solar flux and precipitation). Multiple correlations of daily pollen counts with simultaneous values of daily meteorological variables do not show annual course for Ambrosia, but do show definite trends for Populus and Poaceae. Results received using the two methods revealed characteristic similarities. For all the three taxa, the continental rainfall peak and additional local showers in the growing season can strengthen the weight of the current meteorological elements. However, due to the precipitation, big amount of water can be stored in the soil contributing to the effect of the past climate elements during dry periods. Higher climate sensitivity (especially water sensitivity) of the herbaceous taxa (Ambrosia and Poaceae) can be definitely established compared to the arboreal Populus. Separation of the weight of the current and past weather conditions for different taxa involves practical importance both for health care and agricultural production.

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Trends in the prevalence of asthma and allergic rhinitis in Italy between 1991 and 2010

Cited by 189 publications

References 46 publications

Adult-onset asthma: is it really different?

Adult-onset asthma: is it really different?

Incidence of food anaphylaxis in Piemonte region (Italy): data from registry of Center for Severe Allergic Reactions

Plants remember past weather: a study for atmospheric pollen concentrations of Ambrosia, Poaceae and Populus

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