Trends in the Treatment of Dupuytren Disease in the United States Between 2007 and 2014

Lipman, Marc D.; Carstensen, S. Evan; Deal, Dwight D.

doi:10.1177/1558944716647101

Cited by 47 publications

(49 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…La tendencia de nuestros cirujanos parece orientar a la preferencia en la actualidad hacia técnicas mínimamente invasivas en el tratamiento de la ED, ya que permiten una rápida recuperación del paciente con el mínimo impacto, dejando solo las técnicas más exigentes para aquellos casos graves y de recurrencias marcadas, tal y como opinan diversos autores. 13,14 En cuanto a los casos primarios, hemos observado que los cirujanos participantes con más tiempo de especialistas en cirugía de la mano, tienen una tendencia a escoger CCH como tratamiento para la ED. De igual manera, aquellos que reportan mayor frecuencia de su uso en la práctica habitual tienen mayor probabilidad de seleccionar CCH como método de tratamiento.…”

Section: Discussionunclassified

Current Trends in the Treatment of Dupuytren Disease in Spain

Sanjuán-Cerveró

Herrero

Novoa-Parra

et al. 2020

Revista Iberoamericana de Cirugía de la Mano

View full text Add to dashboard Cite

Objective Assessment of the treatment trends of Spanish surgeons in clinical practice by making clinical assumptions in Dupuytren's disease (DD). Material and Method A survey was sent to the members of the Spanish Society for Surgery of the Hand (Sociedad Española de Cirugía de la Mano, SECMA) posing primary and secondary clinical cases. A relationship is established between the selected treatment, the characteristics of the participating surgeons, and the characteristics of the primary clinical cases. Treatment preferences in recurrences are assessed descriptively. Results In total, 127 surveys were answered. 62.2% of the participants had experience with the use of collagenase and were the basis of the analysis. In primary cases, surgeons with more practice time tended to choose collagenase as treatment for DD. Surgeons who reported higher frequency of collagenase use (67.4% vs. 25.7%) were up to 6 times more likely to indicate such treatment. The patient's age under 50 years was the variable with the greatest association strength for the choice of collagenase treatment (OR = 3.8; CI95% 1.9–7.6). In recurrences, among all clinical cases, the most common answer given by the surgeons was partial fasciectomy. Conclusions Partial fasciectomy continues to be the most widely used treatment for DD in Spain. In primary cases, collagenase is an alternative adopted by experienced surgeons, and in treatments for young patients. In recurrences, partial fasciectomy is the preferred technique.

show abstract

Section: Discussionunclassified

Current Trends in the Treatment of Dupuytren Disease in Spain

Sanjuán-Cerveró

Herrero

Novoa-Parra

et al. 2020

Revista Iberoamericana de Cirugía de la Mano

View full text Add to dashboard Cite

show abstract

“…This database has been used in a variety of clinical studies. [10][11][12][13] The database provides an option for longitudinal tracking based on the date of a diagnosis, procedure, imaging event, lab result and/or a prescription medication. This function was useful for our particular analysis because it allowed us to track the amount of imaging paid for by Humana insurance after the diagnosis of AIS and/or LBP.…”

Section: Introductionmentioning

confidence: 99%

The Use of Magnetic Resonance Imaging and Plain Radiographs Among Adolescents With Back Pain and Adolescent Idiopathic Scoliosis

et al. 2018

View full text Add to dashboard Cite

Background: Low back pain (LBP) and adolescent idiopathic scoliosis (AIS) are common pediatric diagnoses. The workup for these diagnoses can be highly variable and can use significant health care resources. There has been no analysis to date on the use of imaging for workup of AIS and/or LBP.Methods: The Humana Private Payer Database was queried for clinical and financial information for patients with AIS and/or LBP using International Classification of Diseases (ICD-9) for LBP and AIS. Current procedural terminology codes related to magnetic resonance imaging (MRI) and radiographs for the thoracolumbar spine were used to identify patients with LBP and/or AIS that used these diagnostic imaging modalities. Only patients ages 10 to 19 years were included in this analysis.Results: The total number of patients with AIS and LBP was 18 696 and 56 560, respectively. Thoracolumbar imaging was used within the workup for 71.76% and 45.53% of patients with AIS alone and LBP alone, respectively. MRI was used for 2.92% and 9.53% of patients with AIS alone and LBP alone, respectively. Radiographic imaging was used for 71.06% and 42.63% for AIS alone and LBP alone, respectively. There was minimal variation among regions in use of MRI for AIS. For patients with LBP, the diagnosis with the highest use of MRI was ''sciatica'' (29.07%). Patients with both LBP and AIS had statistically higher rates of imaging (91.04%), MRI (18.99%), and radiographs (89.71%). Among patients with an MRI, 20.87% never had a radiograph. Reimbursement per patient for radiographs was $164 and $239 for AIS and LBP, respectively. Reimbursement per patient for MRI was $1,263 and $1,882 for AIS and LBP, respectively.Conclusions: There is substantial use of both MRI and radiographs for adolescents with LBP and/or AIS. Clinicians should be aware of the impact these diagnostic tests have on the patient and the overall health care system.

show abstract

“…9 For more severe cases, 4 main treatment options are available, including fasciectomy, open fasciotomy, percutaneous needle aponeurotomy, and collagenase Clostridium histolyticum (CCH) (Xiaflex, Endo Pharmaceuticals, Inc, Malvern, PA) injection, with the goal of improving finger motion and function. 4,9 Fasciectomy has been the standard treatment for DC, involving surgical excision of the palmar fascia and, in some cases, fascia of the digit. Collagenase C histolyticum was approved in the US in 2010 to treat adult patients with DC with a palpable cord; it has become an established nonsurgical treatment alternative.…”

mentioning

confidence: 99%

“…Currently, fasciectomy and CCH are the most commonly used treatments for DC in the US and therefore were the focus of the current study. 4 Since the introduction of CCH, use of both fasciectomy and fasciotomy for DC have decreased, whereas CCH injections have increased at a similar rate. 4 Clinical trials comparing CCH and fasciectomy are limited.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Cost per Episode of Care With Collagenase Clostridium histolyticum Versus Fasciectomy for Dupuytren Contracture: A Real-World Claims Database Analysis

Camper

Divino

Hurley

et al. 2019

Journal of Hand Surgery Global Online

View full text Add to dashboard Cite

Purpose: To quantify the total cost for a 3-month episode of care after treatment with collagenase Clostridium histolyticum (CCH) (Xiaflex) versus fasciectomy for Dupuytren contracture (DC) in the United States. Methods: Adult patients treated for DC (single finger only) with either CCH or fasciectomy from January, 2012 to June, 2016 were identified (the first treatment was the index date) from the IQVIA Real-World Data Adjudicated Claims-US Database. Patients had continuous health plan enrollment 360 days or more pre-index (pre-index) and 90 days or more post-index (follow-up), and one or more pre-index medical claims with a DC diagnosis (International Classification of Diseases, Ninth Revision, Clinical Modification 728.6; International Classification of Diseases, 10th Revision, Clinical Modification M72.0). Patients with pre-index treatment for DC were excluded. The primary outcome was the comparison of allcause and DC-specific health care costs paid by the health plan over the 3-month follow-up. We defined DC-specific as claims with a DC diagnosis, DC-related therapies, and all claims associated with the index date and day after. Generalized linear models compared adjusted all-cause and disease-specific total costs. Results: A total of 1,654 CCH and 2,745 fasciectomy patients were identified (mean age, 59.7 and 58.0 years; 81.8% and 74.4% male; respectively). Fasciectomy patients had higher mean total all-cause costs compared with CCH patients in the follow-up

show abstract

Trends in the Treatment of Dupuytren Disease in the United States Between 2007 and 2014

Cited by 47 publications

References 31 publications

Current Trends in the Treatment of Dupuytren Disease in Spain

Current Trends in the Treatment of Dupuytren Disease in Spain

The Use of Magnetic Resonance Imaging and Plain Radiographs Among Adolescents With Back Pain and Adolescent Idiopathic Scoliosis

Cost per Episode of Care With Collagenase Clostridium histolyticum Versus Fasciectomy for Dupuytren Contracture: A Real-World Claims Database Analysis

Contact Info

Product

Resources

About