“…Nonetheless, the isolation and detection of CTCs are made possible with the advancement in microfluidics technology. The recent trends in microfluidics involve the integration of multiple traditional laboratory procedures into an automated micro total analysis system (µTAS) or lab-on-a-chip for a myriad of biological applications such as cancer screening, disease diagnosis, and drug test [72]. The miniaturization of these labon-a-chip devices offers the benefits of requiring less sample volume, faster analysis, precise fluid handling, and reduced biological and chemical wastes [73].…”