Trends of the Prevalence of Pre-gestational Diabetes in 2030 and 2050 in Belgrade Cohort

Abstract

The aim of this study was to analyze the trends in diabetes in pregnancy in Belgrade, Serbia for the period of the past decade and forecast the number of women with pre-gestational diabetes for the years 2030 and 2050. The study included the data on all pregnant women with diabetes from the registry of the deliveries in Belgrade, by the City Institute of Public Health of Belgrade, Serbia for the period between 2010 and 2020 and the published data on the deliveries on the territory of Belgrade. During the examined period the total number of live births in Belgrade was 196,987, and the prevalence of diabetes in pregnancy was 3.4%, with the total prevalence of pre-gestational diabetes of 0.7% and overall prevalence of GDM of 2.7%. The average age of women in our study was significantly lower in 2010 compared to 2020. The forecasted prevalence of pre-gestational diabetes among all pregnant women for 2030 is 2% and 4% for 2050 in our cohort. Our study showed that the prevalence of pre-gestational diabetes has increased both among all pregnant women and among women with diabetes in pregnancy in the past decade in Belgrade, Serbia and that it is expected to increase further in the next decades and to further double by 2050.

Maternofetal interaction and modulation in creating a new population: A review of current evidence on the relationship between fetal nutrition and the development of chronic diseases later in life

“…Naglašava se značaj potencijalnog razvoja dijabetesa u kasnijem životnom dobu jer je aktuelan trend povećavanja njegove prevalence kod odraslih osoba, samim tim i kod žena, zbog potencijalne trudnoće opterećene ovim komorbiditetom. Prevalenca pregestacionog dijabetesa kod trudnica povećala se u prethodnoj deceniji u Beogradu, i očekuje se njen dalji porast, kao i to da će se duplirati do 2050. godine [23].…”

“…Oni su ispitivali senzitivnost na insulin i sekreciju insulina u vezi sa veličinom tela na rođenju kod muškaraca i tial pregnancy burdened by this comorbidity. The prevalence of pregestational diabetes in pregnant women has increased in the past decade in Belgrade and it is expected to continue rising, and even to double by 2050 [23]. Also, it has been shown that women with type 1 diabetes have an increased risk of pregnancy complications and unfavorable neonatal outcomes compared to those with type 2 diabetes or gestational diabetes mellitus [24].…”

Early Gestational Blood Markers to Predict Preeclampsia Complicating Gestational Diabetes Mellitus

“…2 With the increasing prevalence of obesity and lifestyle changes, the prevalence of GDM has also significantly increased two to three times in approximately 10 years. 3 In recent years, with the lowering of the diagnostic threshold for GDM, the regulation of diet and exercise, and the strengthening of fetal monitoring, fetal complications caused by GDM have been properly managed. However, maternal complications, such as gestational hypertension and preeclampsia (PE), have not received enough attention.…”