Trial for Preparation and Evaluation of Autogenous Killed Vaccine Against Some Locally Isolated Strains of Salmonella enterica from Chickens in Egypt

doi:10.47278/journal.ijvs/2022.209

Cited by 2 publications

(1 citation statement)

References 33 publications

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“…Most of these foodborne illnesses are a problem for worldwide public health because they are brought on by pathogenic bacteria, viruses and parasites (3,4). One of the main causes of foodborne diseases is Salmonellosis infection, which is brought on by a species of Salmonella (5,6). Salmonella has long been recognized as an important zoonotic pathogen of economic importance in animals and humans.…”

Section: Introductionmentioning

confidence: 99%

Phytochemicals: potential alternative strategy to fight Salmonella enterica serovar Typhimurium

Almuzaini

2023

Front. Vet. Sci.

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The rise of multidrug resistant (MDR) microorganisms is a great hazard worldwide and has made it difficult to treat many infectious diseases adequately. One of the most prevalent causes of outbreaks of foodborne illness worldwide is Salmonella. The ability of this and other harmful bacteria to withstand antibiotics has recently proven crucial to their effective control. Since the beginning of time, herbal medicines and phytochemicals have been employed for their potent antibacterial action and there is a growing trend toward the production of plant based natural products for the prevention and treatment of pathogenic infections. Numerous phytochemicals have been proven effective against the molecular determinants responsible for attaining drug resistance in pathogens like efflux pumps, membrane proteins, bacterial cell communications and biofilms. The medicinal plants having antibacterial activity and antibiotics combination with phytochemicals have shown synergetic activity against Salmonella enterica serovar Typhimurium. The inhibitory effects of tannins on rumen proteolytic bacteria can be exploited in ruminant nutrition. Improved control of the rumen ecology and practical use of this feed additive technology in livestock production will be made possible by a better knowledge of the modulatory effects of phytochemicals on the rumen microbial populations in combination with fermentation. This review focuses on the development of antibacterial resistance in Salmonella, the mechanism of action of phytochemicals and the use of phytochemicals against S. enterica serovar Typhimurium. The advances and potential future applications of phytochemicals in the fight against resistant are also discussed.

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Section: Introductionmentioning

confidence: 99%

Phytochemicals: potential alternative strategy to fight Salmonella enterica serovar Typhimurium

Almuzaini

2023

Front. Vet. Sci.

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Efficacy improvement of tri-serotypes vaccine for Salmonella using nanomaterial-based adjuvant in chicken

Ibrahim,

Mohammed,

Sayed

et al. 2024

Beni-Suef Univ J Basic Appl Sci

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Background This study aimed to develop a vaccine for controlling salmonellosis, a zoonotic disease affecting both humans and chicken, by employing Fe2O3 ferrous iron oxide (FNPs), silicon dioxide (SiNPs), carboxymethyl chitosan (C.CS NPs), and FNPs-chitosan (FCNPs) nanocomposite as immunological adjuvants. The immune response of vaccinated chicken was assessed through ELISA and challenge tests. Results The hydrodynamic diameters of Fe2O3, Fe2O3-CS, C.CS, and SiO2 NPs were found to be 81.95 ± 14.95, 137.1 ± 20.5, 32.86 ± 14.05, and 15.64 ± 3.6 nm, respectively. The incorporation of nanoparticles into the vaccine formulation significantly enhanced its efficacy by eliciting a robust immune response. According to the study, FNPs, SiNPs, C.CS NPs, and FCNPs can be used as immunological adjuvants to strengthen chicken’s immune systems and help prevent salmonellosis. By gradually raising antibody titers, all five vaccine formulations successfully stimulated an immunological response against Salmonella in vaccinated chicken. The size of the immunological response, however, differed amongst the various vaccination formulations. The SiNPs group had the highest antibody titer, followed by the locally administered vaccine. Conclusions These findings suggest that the use of silicon dioxide SiNPs as a vaccine delivery system could enhance the immune response to Salmonella in chicken. Overall, the study demonstrates that the use of adjuvanted vaccines with nanomaterials, particularly SiNPs, has significantly increased the protection rate from 67 to 93.3% when compared to the locally used vaccine, which had a protection rate of 83%.

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Trial for Preparation and Evaluation of Autogenous Killed Vaccine Against Some Locally Isolated Strains of Salmonella enterica from Chickens in Egypt

Cited by 2 publications

References 33 publications

Phytochemicals: potential alternative strategy to fight Salmonella enterica serovar Typhimurium

Phytochemicals: potential alternative strategy to fight Salmonella enterica serovar Typhimurium

Efficacy improvement of tri-serotypes vaccine for Salmonella using nanomaterial-based adjuvant in chicken

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