Triazine Herbicides in the Environment

Klementová, Šárka; Keltnerova, Lucie

doi:10.5772/60858

Cited by 17 publications

(9 citation statements)

References 73 publications

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“…In certain studies, human exposure to high doses of atrazine can cause loss of body weight. Nevertheless, several epidemiological studies done with workers usually exposed to triazine indicate that these compounds show no potentials of been carcinogenic to the workers [20]. Furthermore, via analyses of different studies, it was observed that, though the chloro-s-triazine interferes in the endocrine responses of different species of mammals, their impending impact on humans seems to be primarily related to reproduction and development and not with human carcinogenesis [21].…”

Section: Effect Of Chemical Pesticides On Safety Of Food: Research St...mentioning

confidence: 99%

Chemical Pesticides and Food Safety

Nwosu¹,

John²

2022

Insecticides - Impact and Benefits of Its Use for Humanity

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Pesticides are usually applied to protect crops against insects and other pests. These pesticides of synthetic origin are potentially toxic to humans and can have both acute and chronic health effects, depending on the quantity and ways in which a person is exposed. They play significant roles in food production as they protect or increase yields due to less attack by insect pests. This is particularly important in countries that face food security challenges. The general population—who are not in the area where pesticides are used—is exposed to significantly lower levels of chemical insecticide residues through food and water. Chemical pesticides are among the leading causes of death by self-poisoning, in particular in low- and middle-income countries. Adverse effects from these synthetic pesticides occur only above a certain safe level of exposure. When people come into contact with large quantities of it in food, it may cause acute poisoning or long-term health effects, including cancer and adverse effects on reproduction. Production, distribution, and use of pesticides require strict regulation and control. Regular monitoring of residues in food and the environment is also required. Best among all is the promotion and adoption of bio-insecticides as a better alternative to chemical insecticides.

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Section: Effect Of Chemical Pesticides On Safety Of Food: Research St...mentioning

confidence: 99%

Chemical Pesticides and Food Safety

Nwosu¹,

John²

2022

Insecticides - Impact and Benefits of Its Use for Humanity

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“…The major commercial symmetrical triazines are further divided into chloro-s-triazines (atrazine, propazine, terbutylazine), thiomethyl-s-triazines (ametryn, terbutryn), and methoxy-s-triazine (prometon) (58). Recent years saw a growing concern about the toxicity and environmental persistence and mobility of triazines and their metabolites (59). Atrazine has been used extensively, mainly due to its low cost and ease of application and is the most common contaminant of groundwater and surface water.…”

Section: Triazine Herbicidesmentioning

confidence: 99%

Redox imbalance caused by pesticides: a review of OPENTOX-related research

Čermak

Pavičić

Želježić

2018

Archives of Industrial Hygiene and Toxicology

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Pesticides are a highly diverse group of compounds and the most important chemical stressors in the environment. Mechanisms that could explain pesticide toxicity are constantly being studied and their interactions at the cellular level are often observed in well-controlled in vitro studies. Several pesticide groups have been found to impair the redox balance in the cell, but the mechanisms leading to oxidative stress for certain pesticides are only partly understood. As our scientific project "Organic pollutants in environment - markers and biomarkers of toxicity (OPENTOX)" is dedicated to studying toxic effects of selected insecticides and herbicides, this review is focused on reporting the knowledge regarding oxidative stress-related phenomena at the cellular level. We wanted to single out the most important facts relevant to the evaluation of our own findings from studies conducted on in vitro cell models.

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“…Other widely used 1,3,5-triazines are, e.g., cyanuric chloride (2,4,6-trichloro-1,3,5-triazine) and 6-alkyl/aryl-1,3,5-triazine-2,4-diamines. Triazine-based agents such as atrazine, ametryn, prometryn, cyanazine, propazine, simazine, terbuthylazine and terbutryn are highly effective herbicides [3], unfortunately also with strong adverse impacts on humans and the environment [4][5][6][7][8][9]. On the other hand, 1,3,5-triazines represent a remarkable platform for the design of potential drugs, especially with anti-infective (antiviral, antibacterial, antimycobacterial, antifungal, antiprotozoal, anthelmintic) and anticancer effects, but also with anti-inflammatory, antidiabetic, antioxidant, antiulcer, anticonvulsant and cardioprotective activities, depending on the specific substitution of the 1,3,5-triazine scaffold [1,[10][11][12][13][14].…”

Section: Introductionmentioning

confidence: 99%