Abstract. Das G, Thou K, Mondal P, Meeran SM. 2022. Review: Ethnomedicinal plants used for wound healing and dermatological problem in the North-Eastern Hill Region of India. Asian J Ethnobiol 5: 102-119. Wound healing is a complex process that facilitates tissue cohesion and homeostasis renewal. Medicinal plants have several bioactive compounds and play a principal role in healing and curing human and animal diseases. In our review, we collected ethnobotanical information mostly from Nagaland, a North-Eastern state of India, from various ethnic groups through personal communication, articles, surveys, and sources. In this study, we selected 26 plant species belonging to 20 families categorized as herbs (15 species), shrubs (5 species), trees (4 species), and climbers (2 species) with scientifically demonstrated medicinal properties or reported from ethnic groups on wound healing, dermatological problem, other numerous diseases and disorders relating to the urinary system, inflammation, tumors, diabetes, diarrhea, gastritis, scabies, skin sores, animal/insect bites, parasitic related problems, and rheumatism. They have been compiled and reviewed. Medicinal plants are considered efficacious adjuvants or alternatives to conventional therapies to treat various diseases, and the use of medicinal plants and their products to cure different ailments was reported and recorded. Our review will help create awareness about using medicinal plants and alternative medicine to ameliorate dermatological problems and treat various diseases in humans and animals.