Tribromoisocyanuric acid as a useful oxidant for the synthesis of 1,3-diynes via Glaser coupling

Azolium Aurates as Pre-Catalysts for the Oxidative Coupling of Terminal Alkynes under Mild Conditions

“…In general, the typical methods of synthesizing conjugate diynes include the Glaser–Hay and the Cadiot–Chodkiewicz couplings. The metals that have been explored as possible catalysts for these transformations include Cu, Pd, Co, and Ni, but Cu is the most widely used . However, those traditional coupling reactions usually require high catalyst loading, large amounts of base, elevated reaction temperatures, and/or alkyne pre-functionalization .…”