Tributylborane in the synthesis of graft copolymers of collagen and polymethyl methacrylate

Kuznetsova, Yu. L.; Морозова, Е. А.; Sustaeva, K. S.; Маркин, А. В.; Mitin, A. V.; Батенькин, М. А.; Salomatina, E. V.; Shurygina, M. P.; Gushchina, Ksenya; Pryazhnikova, M. I.; Семенычева, Л. Л.

doi:10.1007/s11172-022-3424-3

Cited by 10 publications

(12 citation statements)

References 26 publications

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“…The skin gelatin of tilapia and grass carp extracted with trypsin in this study has good emulsifying properties. One possible reason is that trypsin has split the collagen into more short-chain peptides containing more low-molecular-weight fragments [ 27 , 28 ], which provide more electriferous groups at the ends of polypeptides and increase the area of the contact surface, thus improving the emulsifying properties of gelatin. Fish skin gelatin prepared with this method can be used as a foaming agent or an emulsifying agent in such application fields as food, pharmacy, and medical technology [ 29 ].…”

Section: Discussionmentioning

confidence: 99%

Influences of Trypsin Pretreatment on the Structures, Composition, and Functional Characteristics of Skin Gelatin of Tilapia, Grass Carp, and Sea Perch

Ruan

Chen

et al. 2023

Marine Drugs

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Fish skin gelatin is an important functional product in the food, cosmetics, and biomedicine industries, and establishing a green and effective fish skin gelatin extraction method is an effective way to obtain high-quality gelatin and improve its production efficiency. In this study, a trypsin method was used to extract the skin gelatin of sea perch, tilapia, and grass carp, and the microstructures of skin gelatin of these three fish species were analyzed, with such functional characteristics as thermal stability, gel strength, and emulsifying properties measured. The study results show that the skin gelatin of sea perch and tilapia obtained through the trypsin method has a relatively big molecular mass, a dense network structure, and a stable trihelix conformation. In addition, the skin gelatin of these three fish species has a relatively high β-turn content in the secondary structure, good gel strength, and water absorption properties. The compositions of the collagen-associated proteins in the skin gelatins of these three fish species extracted with the trypsin method are significantly different from each other, with positive effects of decorin and biglycan on the stability of the network structure of gelatin and a certain damaging effect of metalloendopeptidase on the network structure of gelatin. The skin gelatin of tilapia has high thermal stability and good emulsifying performance. Therefore, this gelatin type has bright application prospects in such fields as food processing, cosmetics, and drug development. In contrast, the skin gelatin of grass carp has poor functional properties. Therefore, there are significant differences among the structures and functions of skin gelatin extracted from different kinds of fish through the trypsin method. This finding has provided a useful reference for the production of customized fish gelatin according to demand.

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Section: Discussionmentioning

confidence: 99%

Influences of Trypsin Pretreatment on the Structures, Composition, and Functional Characteristics of Skin Gelatin of Tilapia, Grass Carp, and Sea Perch

Ruan

Chen

et al. 2023

Marine Drugs

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“…40 Copolymers of hydroxoethyl methacrylate with itaconic acid were synthesized in the presence of collagen and the corresponding biocomposites were obtained. 41 Graft copolymers of gelatin 42 and collagen 43 with acrylamide (AD) and methylmethacrylate, 44 as well as collagen with butylacrylate 45 have been synthesized. The sample of the graft copolymer of collagen and PAA, obtained at 60 C, has higher mechanical properties compared to other tested samples.…”

Section: Introductionmentioning

confidence: 99%

“…Graft copolymers of gelatin 42 and collagen 43 with acrylamide (AD) and methylmethacrylate, 44 as well as collagen with butylacrylate 45 have been synthesized. The sample of the graft copolymer of collagen and PAA, obtained at 60°C, has higher mechanical properties compared to other tested samples.…”

Section: Introductionmentioning

confidence: 99%

Graft copolymers of collagen and acrylic monomers—Reagents for sizing of cotton yarn

Rafikov,

Ibodulloyev,

Yasinskaya

et al. 2024

Polymer Engineering & Sci

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A new highly effective sizing reagent based on grafted collagen copolymers has been proposed for cotton yarn. The copolymers were synthesized by reacting an aqueous solution of collagen with acrylic monomers—acrylic, matacrylic acids, and their amides in the presence of potassium persulfate. Based on Scanning electron microscopy ‐ Energy dispersive (SEM‐EDS) analysis data, the composition of the copolymers was determined. Unsaturated acids are more actively grafted onto collagen than their amides. When a polymer film is formed from a solution of a collagen copolymer with (meth)acrylic acid, microcracks appear on the surface of the sample; microcracks are absent in films of copolymers with (meth)acrylamide. Films of copolymers, especially methacrylamide, are quite flexible and contribute to a significant improvement in the properties of the yarn. The tensile strength of yarn sized with copolymers increases by 20%–65% compared to unsized yarn, and by 13%–38% compared to yarn sized with a starch solution. At the same time, the relative tensile elongation of the experimental yarn improves by 14%–58%, while this property of starch‐size yarn deteriorates by 14%–22% compared to unsized yarn. The complete removal of graft copolymers from the surface of the yarn in the process of biochemical desizing using the enzyme protease is shown.Highlights Graft copolymerization of (meth)acrylamide with collagen was carried out. Grafting is initiated by the interaction of collagen with potassium persulfate. The synthesized copolymers are effective sizing reagents for cotton yarn. The copolymer with poly(meth)acrylamide forms a flexible and stable film. The protease enzyme completely removes the size from the surface of the yarn.

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Section: Introductionmentioning

confidence: 99%

“…Organoborane compounds are used to synthesize grafted copolymers [ 32 , 33 , 34 ]. Tributyl borane makes it possible to obtain copolymers of collagen and poly(methyl methacrylate) [ 32 , 33 ], triethyl borane–copolymer of collagen and poly(butyl acrylate) [ 34 ], and the combination of triethyl borane and p –quinone—a copolymer of starch and poly(methyl acrylate) [ 35 ]. At the same time, alkylborane in the composition of various initiators makes it possible to obtain grafted copolymers both by “grafting from” [ 32 , 33 , 34 ] or “grafting to” [ 35 ].…”

Section: Introductionmentioning

confidence: 99%

Scaffold Chemical Model Based on Collagen—Methyl Methacrylate Graft Copolymers

Kuznetsova,

Gushchina,

Lobanova

et al. 2023

Polymers

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Polymerization of methyl methacrylate (MMA) in aqueous collagen (Col) dispersion was studied in the presence of tributylborane (TBB) and p-quinone: 2,5-di-tert-butyl-p-benzoquinone (2,5-DTBQ), p-benzoquinone (BQ), duroquinone (DQ), and p-naphthoquinone (NQ). It was found that this system leads to the formation of a grafted cross-linked copolymer. The inhibitory effect of p-quinone determines the amount of unreacted monomer, homopolymer, and percentage of grafted poly(methyl methacrylate) (PMMA). The synthesis combines two approaches to form a grafted copolymer with a cross-linked structure—“grafting to” and “grafting from”. The resulting products exhibit biodegradation under the action of enzymes, do not have toxicity, and demonstrate a stimulating effect on cell growth. At the same time, the denaturation of collagen occurring at elevated temperatures does not impair the characteristics of copolymers. These results allow us to present the research as a scaffold chemical model. Comparison of the properties of the obtained copolymers helps to determine the optimal method for the synthesis of scaffold precursors—synthesis of a collagen and poly(methyl methacrylate) copolymer at 60 °C in a 1% acetic acid dispersion of fish collagen with a mass ratio of the components collagen:MMA:TBB:2,5-DTBQ equal to 1:1:0.015:0.25.

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Tributylborane in the synthesis of graft copolymers of collagen and polymethyl methacrylate

Cited by 10 publications

References 26 publications

Influences of Trypsin Pretreatment on the Structures, Composition, and Functional Characteristics of Skin Gelatin of Tilapia, Grass Carp, and Sea Perch

Influences of Trypsin Pretreatment on the Structures, Composition, and Functional Characteristics of Skin Gelatin of Tilapia, Grass Carp, and Sea Perch

Graft copolymers of collagen and acrylic monomers—Reagents for sizing of cotton yarn

Scaffold Chemical Model Based on Collagen—Methyl Methacrylate Graft Copolymers

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