Tricarbonylrhenium(I) complexes with heterodentate ligands based on functionalized amides: Synthesis, structural features, and cytotoxic activity

Tuning the reaction pathways of phenanthroline-Schiff bases: routes to novel phenanthroline ligands

“…17 In a related context there is substantial interest in developing rhenium(I) tricarbonyl complexes for their anticancer activity. [18][19][20][21] Here we report the novel and simple one-pot route to making ascididemin analogues from readily available starting materials, the full structural characterisation of methyl 7-oxo-4-phenyl-7H-pyrido[4,3,2-de][1,10]phenanthroline-5-carboxylate (1a) and preliminary studies on forming a rhenium(I) tricarbonyl complex with its propyl ester analogue (1b). We also give some insights into the factors that control the direction of this unusual reaction to form the pyrido-ligand product.…”