Triceps Skinfold Thickness Is Associated With Lumbar Bone Mineral Density in Peritoneal Dialysis Patients

Abstract

Anthropometric measurements, including body mass index (BMI), body weight and total fat mass are associated with the bone mineral density (BMD) in the general population. Compared to that in the general population, BMD was lower in dialysis patients. However, the association between anthropometric measurements and BMD is not well-established among peritoneal dialysis (PD) patients. To study this, we conducted a cross-sectional study in 48 chronic PD patients. Anthropometric parameters, biochemical data, and BMD measured by dual energy X-ray absorptiometry in lumbar vertebrae (L2-L4) were collected. Among these PD patients, eight patients (16.7%) had osteoporosis and 22 patients (45.8%) osteopenia, while 18 patients were normal. Older age, decreased height, lower body weight, BMI, triceps skinfold thickness (TSF), mid-arm fat area (MAFA), and higher adiponectin levels were observed in our patients with lower lumbar T-scores. Height, body weight, waist circumference, BMI, body fat mass, TSF, mid-arm circumference, MAFA, and serum phosphorus levels were positively, while age, adiponectin levels were negatively correlated with lumbar BMD levels. According to our multivariate forward stepwise linear regression analysis, TSF (R change = 0.080, P = 0.017) and body weight (R change = 0.333, P = 0.002) were both correlated with low lumbar BMD. In conclusion, either TSF or body weight in our chronic PD patients was proved to be an independent predictor for osteolytic bone lesions.

Resveratrol attenuates type 2 diabetes mellitus by mediating mitochondrial biogenesis and lipid metabolism via Sirtuin type 1

“…A number of proteins, including mitochondrial biogenesis-related nuclear respiratory factor (NRF), mitochondrial transcription factor A (mtTFA), lipid metabolism-associated carnitine palmitoyltransferase 1 (CPT-1), acetyl-CoA carboxylase (ACC), long-chain acyl-CoA dehydrogenase (LCAD), β-cells-associated pancreatic duodenal homeobox-1 gene (PDX-1), mid-arm fat area (MAFA) (8) and INS, are associated with T2DM (9). Resveratrol (RSV), a natural polyphenol found in grapes and red wine (10), may potentially attenuate hepatic steatosis and reduce the risk of patients developing T2DM (11).…”

Low serum adiponectin level is associated with central arterial stiffness in patients undergoing peritoneal dialysis

“…The trained staff measured body weights with patients in light clothing and without shoes to the nearest 0.5 kg, and the height was measured to the nearest 0.5 cm. We calculated the body mass indexes as weight (kg) divided by height squared (m 2 ) [ 16 17 ].…”

“…Serum samples were stored at 4°C and used for biochemical analyses within 1 h of collection. Serum levels of blood urea nitrogen, creatinine, fasting glucose, albumin, total cholesterol, triglyceride, total calcium, and phosphorus were measured using an autoanalyzer (Siemens Advia 1800, Siemens Healthcare GmbH, Henkestr, Germany) [ 16 17 ]. Serum adiponectin (SPI-BIO, Montigny le Bretonneux, France) and intact parathyroid hormone (iPTH) levels (Diagnostic Systems Laboratories, Texas, USA) were measured using a commercially available enzyme immunoassay or enzyme-linked immunosorbent assays, respectively [ 18 19 ].…”

Osteocalcin and carotid–femoral pulse wave velocity in patients on peritoneal dialysis

“…Body weight was measured in light clothing and without shoes to the nearest 0.5 kg; height was measured to the nearest 0.5 cm. Body mass index (BMI) was calculated as weight (kg) divided by height-squared (m 2 ) [12131415].…”